Autor Michel, Martin C.
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Documentos disponibles escritos por este autor (2)
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TÃtulo : Concepts and Principles of Pharmacology : 100 Years of the Handbook of Experimental Pharmacology Tipo de documento: documento electrónico Autores: Barrett, James E., ; Page, Clive P., ; Michel, Martin C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2019 Número de páginas: VIII, 466 p. 100 ilustraciones, 30 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-35362-9 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Palabras clave: FarmacologÃa Ãndice Dewey: 615 Medicina (Farmacología terapéutica) Resumen: Celebrando los 100 años de HEP, este volumen analizará conceptos y descubrimientos farmacológicos clave de los últimos 100 años. Estos descubrimientos han cambiado drásticamente los paradigmas de tratamiento médico de muchas enfermedades y estos conceptos han dado y seguirán dando forma al descubrimiento de nuevos medicamentos. De manera similar, se discutirán las nuevas tecnologÃas que darán forma al futuro de la farmacologÃa y, en consecuencia, de la terapia médica. Nota de contenido: Part 1. A Century of Advances in Pharmacology -- 1. Perspectives of Pharmacology Over the Past 100 years -- 2. Emergent concepts of receptor pharmacology -- 3. The Evolving Landscape of Cancer Therapeutics -- 4. Monoclonal Antibodies: Past, Present and Future -- 5. 100 years of Drug Delivery to the Lungs -- 6. Exploiting the Diversity of Ion Channels: Ion channel Pharmacology for Pain modulation -- 7. Exploiting the Diversity of Ion Channels: Modulation of Ion Channels for Therapeutic Indications -- Part 2. Recent developments and enabling technologies in pharmacology -- 8. Genetically Encoded Fluorescent Calcium and Voltage Indicators -- 9. Mechanistic Image-Based Modeling: Concepts and Applications of Image-Based Modeling -- 10. Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling -- 11. The Microbiome and its Potential for Pharmacology -- 12. Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology -- Part 3. The future of pharmacology -- 13. The future of clinical trial design: The Transition from Hard Endpoints to Value-Based Endpoings -- 14. Placebos and the Placebo Effect in Drug Trials -- 15. Pharmacoepidemiology -- 16. Why are new drugs expensive and how can they stay affordable? . En lÃnea: https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Link: https://biblioteca.umanizales.edu.co/ils/opac_css/index.php?lvl=notice_display&i Concepts and Principles of Pharmacology : 100 Years of the Handbook of Experimental Pharmacology [documento electrónico] / Barrett, James E., ; Page, Clive P., ; Michel, Martin C., . - 1 ed. . - [s.l.] : Springer, 2019 . - VIII, 466 p. 100 ilustraciones, 30 ilustraciones en color.
ISBN : 978-3-030-35362-9
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Palabras clave: FarmacologÃa Ãndice Dewey: 615 Medicina (Farmacología terapéutica) Resumen: Celebrando los 100 años de HEP, este volumen analizará conceptos y descubrimientos farmacológicos clave de los últimos 100 años. Estos descubrimientos han cambiado drásticamente los paradigmas de tratamiento médico de muchas enfermedades y estos conceptos han dado y seguirán dando forma al descubrimiento de nuevos medicamentos. De manera similar, se discutirán las nuevas tecnologÃas que darán forma al futuro de la farmacologÃa y, en consecuencia, de la terapia médica. Nota de contenido: Part 1. A Century of Advances in Pharmacology -- 1. Perspectives of Pharmacology Over the Past 100 years -- 2. Emergent concepts of receptor pharmacology -- 3. The Evolving Landscape of Cancer Therapeutics -- 4. Monoclonal Antibodies: Past, Present and Future -- 5. 100 years of Drug Delivery to the Lungs -- 6. Exploiting the Diversity of Ion Channels: Ion channel Pharmacology for Pain modulation -- 7. Exploiting the Diversity of Ion Channels: Modulation of Ion Channels for Therapeutic Indications -- Part 2. Recent developments and enabling technologies in pharmacology -- 8. Genetically Encoded Fluorescent Calcium and Voltage Indicators -- 9. Mechanistic Image-Based Modeling: Concepts and Applications of Image-Based Modeling -- 10. Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling -- 11. The Microbiome and its Potential for Pharmacology -- 12. Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology -- Part 3. The future of pharmacology -- 13. The future of clinical trial design: The Transition from Hard Endpoints to Value-Based Endpoings -- 14. Placebos and the Placebo Effect in Drug Trials -- 15. Pharmacoepidemiology -- 16. Why are new drugs expensive and how can they stay affordable? . En lÃnea: https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Link: https://biblioteca.umanizales.edu.co/ils/opac_css/index.php?lvl=notice_display&i Good Research Practice in Non-Clinical Pharmacology and Biomedicine / Bespalov, Anton ; Michel, Martin C. ; Steckler, Thomas
TÃtulo : Good Research Practice in Non-Clinical Pharmacology and Biomedicine Tipo de documento: documento electrónico Autores: Bespalov, Anton, ; Michel, Martin C., ; Steckler, Thomas, Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2020 Número de páginas: X, 423 p. 34 ilustraciones, 21 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-33656-1 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Palabras clave: OncologÃa Neurociencia Neurociencias FarmacologÃa CardiologÃa Ãndice Dewey: 615 Medicina (Farmacología terapéutica) Resumen: Este libro de acceso abierto, publicado bajo una licencia CC BY 4.0 en la serie de libros indexados de Pubmed Handbook of Experimental Pharmacology, proporciona información actualizada sobre las mejores prácticas para mejorar el diseño experimental y la calidad de la investigación en farmacologÃa y biomedicina no clÃnica. Nota de contenido: 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers' responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice. En lÃnea: https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Link: https://biblioteca.umanizales.edu.co/ils/opac_css/index.php?lvl=notice_display&i Good Research Practice in Non-Clinical Pharmacology and Biomedicine [documento electrónico] / Bespalov, Anton, ; Michel, Martin C., ; Steckler, Thomas, . - 1 ed. . - [s.l.] : Springer, 2020 . - X, 423 p. 34 ilustraciones, 21 ilustraciones en color.
ISBN : 978-3-030-33656-1
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Palabras clave: OncologÃa Neurociencia Neurociencias FarmacologÃa CardiologÃa Ãndice Dewey: 615 Medicina (Farmacología terapéutica) Resumen: Este libro de acceso abierto, publicado bajo una licencia CC BY 4.0 en la serie de libros indexados de Pubmed Handbook of Experimental Pharmacology, proporciona información actualizada sobre las mejores prácticas para mejorar el diseño experimental y la calidad de la investigación en farmacologÃa y biomedicina no clÃnica. Nota de contenido: 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers' responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice. En lÃnea: https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Link: https://biblioteca.umanizales.edu.co/ils/opac_css/index.php?lvl=notice_display&i
