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Autor Xiao, Junjie |
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Título : Circular RNAs : Biogenesis and Functions Tipo de documento: documento electrónico Autores: Xiao, Junjie, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2018 Número de páginas: VII, 370 p. 41 ilustraciones, 35 ilustraciones en color. ISBN/ISSN/DL: 978-981-1314261-- Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Genética Médica Bioquímica Citología Biología Celular Clasificación: 616.042 Resumen: Este libro proporciona una descripción general esencial del campo de rápido avance de los ARN circulares: ARN recientemente descubiertos que se generan mediante empalme de ARNm precursor y desempeñan funciones reguladoras en muchos procesos biológicos. Aunque muchos aspectos de la biología de los ARN circulares y los mecanismos de regulación genética siguen sin estar claros, se ha descubierto que son abundantes, están conservados evolutivamente y son estables en las células; Además, tienen numerosas funciones potenciales. El libro consta de ocho partes: 1) Una descripción general de los ARN circulares, 2) Bioinformática para los ARN circulares, 3) Biogénesis de los ARN circulares, 4) Mecanismos moleculares y regulación genética de los ARN circulares, 5) Los ARN circulares como posibles biomarcadores de enfermedades, 6 ) ARN circulares y enfermedades humanas, 7) ARN circulares en plantas y arqueas, y 8) Perspectivas de futuro. Dado su enfoque, el libro será especialmente útil para investigadores y estudiantes en los campos de la bioquímica, la biología molecular, la biología celular y la medicina. Nota de contenido: Chapter 1 An overview of circular RNAs -- Chapter 2 RNA-sequencing and the predictions tools for circular RNAs -- Chapter 3 Online databases and circular RNAs -- Chapter 4 Circular RNA splicing -- Chapter 5 Circular RNAs biogenesis in eukaryotes through self-cleaving hammerhead ribozymes -- Chapter 6 Circular RNAs act as miRNA sponges -- Chapter 7 Regulation of transcription by Circular RNAs -- Chapter 8 Functional Analysis of Circular RNAs -- Chapter 9 Circular RNA in Exosomes -- Chapter 10 Circular RNAs in Blood -- Chapter 11 Circular RNA in Saliva -- Chapter 12 Emerging role of circular RNAs as potential biomarkers for the diagnosis of Human Diseases -- Chapter 13 Circular RNAs as novel biomarkers for cardiovascular diseases -- Chapter 14 Circular RNAs as biomarkers for cancer -- Chapter 15 Circular RNAs in cardiovascular diseases -- Chapter 16 Circular RNAs and Neuronal Development -- Chapter 17 Circular RNAs in Cancer -- Chapter 18 Circular RNAs in Brain Physiology and Disease -- Chapter19 Circular RNA and Alzheimer's Disease -- Chapter 20 Circular RNA in Liver: Health and Diseases -- Chapter 21 Circular RNAs in Organ Fibrosis -- Chapter 22 Circular RNAs in Metabolic Diseases -- Chapter 23 Circular RNAs in vascular functions and diseases -- Chapter 24 Functional role of circular RNA in regenerative medicine -- Chapter 25 The role of circular RNAs in cerebral ischemic diseases: ischemic stroke and cerebral ischemia/reperfusion injury -- Chapter 26 CircRNAs in plants -- Chapter 27 Circular RNAs and plant stress responses -- Chapter 28 Prospective advances in circular RNA investigation. Tipo de medio : Computadora Summary : This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs' biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Circular RNAs : Biogenesis and Functions [documento electrónico] / Xiao, Junjie, . - 1 ed. . - Singapore [Malasia] : Springer, 2018 . - VII, 370 p. 41 ilustraciones, 35 ilustraciones en color.
ISBN : 978-981-1314261--
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Genética Médica Bioquímica Citología Biología Celular Clasificación: 616.042 Resumen: Este libro proporciona una descripción general esencial del campo de rápido avance de los ARN circulares: ARN recientemente descubiertos que se generan mediante empalme de ARNm precursor y desempeñan funciones reguladoras en muchos procesos biológicos. Aunque muchos aspectos de la biología de los ARN circulares y los mecanismos de regulación genética siguen sin estar claros, se ha descubierto que son abundantes, están conservados evolutivamente y son estables en las células; Además, tienen numerosas funciones potenciales. El libro consta de ocho partes: 1) Una descripción general de los ARN circulares, 2) Bioinformática para los ARN circulares, 3) Biogénesis de los ARN circulares, 4) Mecanismos moleculares y regulación genética de los ARN circulares, 5) Los ARN circulares como posibles biomarcadores de enfermedades, 6 ) ARN circulares y enfermedades humanas, 7) ARN circulares en plantas y arqueas, y 8) Perspectivas de futuro. Dado su enfoque, el libro será especialmente útil para investigadores y estudiantes en los campos de la bioquímica, la biología molecular, la biología celular y la medicina. Nota de contenido: Chapter 1 An overview of circular RNAs -- Chapter 2 RNA-sequencing and the predictions tools for circular RNAs -- Chapter 3 Online databases and circular RNAs -- Chapter 4 Circular RNA splicing -- Chapter 5 Circular RNAs biogenesis in eukaryotes through self-cleaving hammerhead ribozymes -- Chapter 6 Circular RNAs act as miRNA sponges -- Chapter 7 Regulation of transcription by Circular RNAs -- Chapter 8 Functional Analysis of Circular RNAs -- Chapter 9 Circular RNA in Exosomes -- Chapter 10 Circular RNAs in Blood -- Chapter 11 Circular RNA in Saliva -- Chapter 12 Emerging role of circular RNAs as potential biomarkers for the diagnosis of Human Diseases -- Chapter 13 Circular RNAs as novel biomarkers for cardiovascular diseases -- Chapter 14 Circular RNAs as biomarkers for cancer -- Chapter 15 Circular RNAs in cardiovascular diseases -- Chapter 16 Circular RNAs and Neuronal Development -- Chapter 17 Circular RNAs in Cancer -- Chapter 18 Circular RNAs in Brain Physiology and Disease -- Chapter19 Circular RNA and Alzheimer's Disease -- Chapter 20 Circular RNA in Liver: Health and Diseases -- Chapter 21 Circular RNAs in Organ Fibrosis -- Chapter 22 Circular RNAs in Metabolic Diseases -- Chapter 23 Circular RNAs in vascular functions and diseases -- Chapter 24 Functional role of circular RNA in regenerative medicine -- Chapter 25 The role of circular RNAs in cerebral ischemic diseases: ischemic stroke and cerebral ischemia/reperfusion injury -- Chapter 26 CircRNAs in plants -- Chapter 27 Circular RNAs and plant stress responses -- Chapter 28 Prospective advances in circular RNA investigation. Tipo de medio : Computadora Summary : This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs' biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
Título : Exercise for Cardiovascular Disease Prevention and Treatment : From Molecular to Clinical, Part 1 Tipo de documento: documento electrónico Autores: Xiao, Junjie, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2017 Número de páginas: VI, 324 p. 44 ilustraciones, 37 ilustraciones en color. ISBN/ISSN/DL: 978-981-10-4307-9 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Fisiología humana Biología Cardiología Investigación biomédica Clasificación: 612 Medicina (Fisiología humana) Resumen: El libro ofrece una visión general intensiva sobre el ejercicio para la prevención y el tratamiento de enfermedades cardiovasculares, desde la investigación básica hasta la práctica clínica. En primer lugar, el volumen resume la respuesta aguda y crónica al ejercicio. En segundo lugar, se resume la evidencia sobre el ejercicio como medicina para el corazón basada en estudios clínicos e investigaciones básicas. En tercer lugar, se presentan los mecanismos moleculares que median los efectos beneficiosos del ejercicio, incluida la señalización IGF-1-PI3K-AKT, la señalización NO, la señalización C/EBPB-Cited4, los ARN no codificantes, los reguladores epigenéticos, la adaptación de las mitocondrias y los exosomas. Finalmente, se proporcionan la dosis, la prescripción y las perspectivas futuras del ejercicio. Este libro proporcionará una valiosa referencia para investigadores en biología celular, fisiología, así como para médicos, fisioterapeutas en cardiología, medicina deportiva, etc. Nota de contenido: Part I: Overview -- Chapter 1: Physical inactivity and the economic and health burdens due to cardiovascular disease: exercise as medicine (Mark Hamer) -- Part II: Cardiac Exercise Physiology -- Chapter 2: Acute and chronic response to exercise in athletes: the "Supernormal Heart (Antonello D'Andrea) -- Chapter 3: The effects of exercise on cardiovascular biomarkers: new insights, recent data, and applications (Lin Che) -- Chapter 4: Acute and chronic exercise in animal models (Vu Thi Thu) -- Part III: Cardiac Cells Adaptations in Exercise -- Chapter 5 Structural, contractile and electrophysiological adaptations of cardiomyocytes to chronic exercise (Krzesiak A) -- Chapter 6: Formation of new cardiomyocytes in exercise (Liang Shen) -- Chapter 7: Physical exercise can spur beneficial neoangiogenesis and microvasculature remodeling within the heart - our salvation? (Michal Miko) -- Chapter 8 The non-cardiomyocyte cells of heart. their possible roles in exercise-based cardiac regeneration, reparation and remodeling (Ivan Varga) -- Part IV: Exercise benefits the Heart: Basic Science Evidence -- Chapter 9: Myocardial infarction and exercise training: evidence from basic science (Ivana Cinthya Moraes-Silva) -- Chapter 10: Cardiac ischemia/reperfusion injury (Juliana Pereira Borges) -- Chapter 11: Experimental evidences supporting the benefits of exercise training in heart failure (Marcelo H. A. Ichige) -- Chapter 12: Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: possible underlying mechanisms (Ayman M. Mahmoud) -- Chapter 13: Cardiac aging – benefits of exercise, Nrf2 activation and antioxidant signaling (Madhusudhanan Narasimhan) -- Chapter 14: Cardiac fibrosis:the beneficial effects of exercise in cardiac fibrosis (Jan Kyselovič) -- Chapter 15: Physical exercise is a potential "medicine" for atherosclerosis (Jian Yang) -- Chapter 16: Experimental evidences supporting training-induced benefits in spontaneously hypertensive rats (GustavoS. Masson) -- Chapter 17: Exercise training in pulmonary hypertension and right heart failure: insights from pre-clinical studies (Daniel Moreira-Gonçalves) -- Part V: Exercise benefits the Heart: Clinical Evidence -- Chapter 18: Coronary heart disease (Lei Wang) -- Chapter 19: Exercise exerts its beneficial effects on acute coronary syndrome：clinical evidence (Zhuyuan Liu) -- Chapter 20: Exercise-based rehabilitation for heart failure:clinical evidence (Rongjing Ding) -- Chapter 21: The benefits of exercise training on aerobic capacity in patients with Heart Failure and Preserved Ejection Fraction (Danilo Marcelo Leite do Prado) -- Chapter 22: Hypertension and exercise training: evidence from clinical studies (Ivana Cinthya Moraes-Silva) -- Chapter 23: Effects of exercise on arrhythmia (and viceversa): lesson from the Greek mythology (Caterina Lambiase) -- Chapter 24: Exercise and congenital heart disease (Junnan Wang) -- Chapter 25: The Positive Effects of Exercise in Chemotherapy-related Cardiomyopathy (Cavarretta Elena) -- Chapter 26: Clinical evidence of exercise benefits for stroke (Peipei Han) -- Chapter 27: Pulmonary hypertension (Abraham Samuel Babu) -- Chapter 28: Peripheral vascular disease (Basant Elnady) -- Part VI: Molecular Mechanisms -- Chapter 29 Molecular mechanisms (Kate L. Weeks) -- Chapter 30: NO Signaling in the cardiovascular system and exercise (Tiago Fernandes) -- Chapter 31: C/EBPB-CITED4 in exercised heart (Shengguang Ding) -- Chapter 32: MicroRNAs mediate beneficial effects of exercise in heart (Yihua Bei) -- Chapter 33: Exercise training and epigenetic regulation: multilevel modification and regulation of gene expression (Ursula Paula Renó Soci) -- Chapter 34: Exercise-induced mitochondrial adaptations in addressing heart failure (Jubert Marquez) -- Chapter 35: Exosomes mediate the beneficial effects of exercise (Yangxin Li) -- Part VII: Exercise Dosing and Prescription -- Chapter 36: Exercise dosing and prescription-Playing it safe: dangers and prescription(Lei Wang). Tipo de medio : Computadora Summary : The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Exercise for Cardiovascular Disease Prevention and Treatment : From Molecular to Clinical, Part 1 [documento electrónico] / Xiao, Junjie, . - 1 ed. . - Singapore [Malasia] : Springer, 2017 . - VI, 324 p. 44 ilustraciones, 37 ilustraciones en color.
ISBN : 978-981-10-4307-9
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Fisiología humana Biología Cardiología Investigación biomédica Clasificación: 612 Medicina (Fisiología humana) Resumen: El libro ofrece una visión general intensiva sobre el ejercicio para la prevención y el tratamiento de enfermedades cardiovasculares, desde la investigación básica hasta la práctica clínica. En primer lugar, el volumen resume la respuesta aguda y crónica al ejercicio. En segundo lugar, se resume la evidencia sobre el ejercicio como medicina para el corazón basada en estudios clínicos e investigaciones básicas. En tercer lugar, se presentan los mecanismos moleculares que median los efectos beneficiosos del ejercicio, incluida la señalización IGF-1-PI3K-AKT, la señalización NO, la señalización C/EBPB-Cited4, los ARN no codificantes, los reguladores epigenéticos, la adaptación de las mitocondrias y los exosomas. Finalmente, se proporcionan la dosis, la prescripción y las perspectivas futuras del ejercicio. Este libro proporcionará una valiosa referencia para investigadores en biología celular, fisiología, así como para médicos, fisioterapeutas en cardiología, medicina deportiva, etc. Nota de contenido: Part I: Overview -- Chapter 1: Physical inactivity and the economic and health burdens due to cardiovascular disease: exercise as medicine (Mark Hamer) -- Part II: Cardiac Exercise Physiology -- Chapter 2: Acute and chronic response to exercise in athletes: the "Supernormal Heart (Antonello D'Andrea) -- Chapter 3: The effects of exercise on cardiovascular biomarkers: new insights, recent data, and applications (Lin Che) -- Chapter 4: Acute and chronic exercise in animal models (Vu Thi Thu) -- Part III: Cardiac Cells Adaptations in Exercise -- Chapter 5 Structural, contractile and electrophysiological adaptations of cardiomyocytes to chronic exercise (Krzesiak A) -- Chapter 6: Formation of new cardiomyocytes in exercise (Liang Shen) -- Chapter 7: Physical exercise can spur beneficial neoangiogenesis and microvasculature remodeling within the heart - our salvation? (Michal Miko) -- Chapter 8 The non-cardiomyocyte cells of heart. their possible roles in exercise-based cardiac regeneration, reparation and remodeling (Ivan Varga) -- Part IV: Exercise benefits the Heart: Basic Science Evidence -- Chapter 9: Myocardial infarction and exercise training: evidence from basic science (Ivana Cinthya Moraes-Silva) -- Chapter 10: Cardiac ischemia/reperfusion injury (Juliana Pereira Borges) -- Chapter 11: Experimental evidences supporting the benefits of exercise training in heart failure (Marcelo H. A. Ichige) -- Chapter 12: Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: possible underlying mechanisms (Ayman M. Mahmoud) -- Chapter 13: Cardiac aging – benefits of exercise, Nrf2 activation and antioxidant signaling (Madhusudhanan Narasimhan) -- Chapter 14: Cardiac fibrosis:the beneficial effects of exercise in cardiac fibrosis (Jan Kyselovič) -- Chapter 15: Physical exercise is a potential "medicine" for atherosclerosis (Jian Yang) -- Chapter 16: Experimental evidences supporting training-induced benefits in spontaneously hypertensive rats (GustavoS. Masson) -- Chapter 17: Exercise training in pulmonary hypertension and right heart failure: insights from pre-clinical studies (Daniel Moreira-Gonçalves) -- Part V: Exercise benefits the Heart: Clinical Evidence -- Chapter 18: Coronary heart disease (Lei Wang) -- Chapter 19: Exercise exerts its beneficial effects on acute coronary syndrome：clinical evidence (Zhuyuan Liu) -- Chapter 20: Exercise-based rehabilitation for heart failure:clinical evidence (Rongjing Ding) -- Chapter 21: The benefits of exercise training on aerobic capacity in patients with Heart Failure and Preserved Ejection Fraction (Danilo Marcelo Leite do Prado) -- Chapter 22: Hypertension and exercise training: evidence from clinical studies (Ivana Cinthya Moraes-Silva) -- Chapter 23: Effects of exercise on arrhythmia (and viceversa): lesson from the Greek mythology (Caterina Lambiase) -- Chapter 24: Exercise and congenital heart disease (Junnan Wang) -- Chapter 25: The Positive Effects of Exercise in Chemotherapy-related Cardiomyopathy (Cavarretta Elena) -- Chapter 26: Clinical evidence of exercise benefits for stroke (Peipei Han) -- Chapter 27: Pulmonary hypertension (Abraham Samuel Babu) -- Chapter 28: Peripheral vascular disease (Basant Elnady) -- Part VI: Molecular Mechanisms -- Chapter 29 Molecular mechanisms (Kate L. Weeks) -- Chapter 30: NO Signaling in the cardiovascular system and exercise (Tiago Fernandes) -- Chapter 31: C/EBPB-CITED4 in exercised heart (Shengguang Ding) -- Chapter 32: MicroRNAs mediate beneficial effects of exercise in heart (Yihua Bei) -- Chapter 33: Exercise training and epigenetic regulation: multilevel modification and regulation of gene expression (Ursula Paula Renó Soci) -- Chapter 34: Exercise-induced mitochondrial adaptations in addressing heart failure (Jubert Marquez) -- Chapter 35: Exosomes mediate the beneficial effects of exercise (Yangxin Li) -- Part VII: Exercise Dosing and Prescription -- Chapter 36: Exercise dosing and prescription-Playing it safe: dangers and prescription(Lei Wang). Tipo de medio : Computadora Summary : The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
Título : Exercise for Cardiovascular Disease Prevention and Treatment : From Molecular to Clinical, Part 2 Tipo de documento: documento electrónico Autores: Xiao, Junjie, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2017 Número de páginas: VII, 387 p. 39 ilustraciones, 33 ilustraciones en color. ISBN/ISSN/DL: 978-981-10-4304-8 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Fisiología humana Biología Cardiología Investigación biomédica Clasificación: 612 Medicina (Fisiología humana) Resumen: El libro ofrece una visión general intensiva sobre el ejercicio para la prevención y el tratamiento de enfermedades cardiovasculares, desde la investigación básica hasta la práctica clínica. En primer lugar, el volumen resume la respuesta aguda y crónica al ejercicio. En segundo lugar, se resume la evidencia sobre el ejercicio como medicina para el corazón basada en estudios clínicos e investigaciones básicas. En tercer lugar, se presentan los mecanismos moleculares que median los efectos beneficiosos del ejercicio, incluida la señalización IGF-1-PI3K-AKT, la señalización NO, la señalización C/EBPB-Cited4, los ARN no codificantes, los reguladores epigenéticos, la adaptación de las mitocondrias y los exosomas. Finalmente, se proporcionan la dosis, la prescripción y las perspectivas futuras del ejercicio. Este libro proporcionará una valiosa referencia para investigadores en biología celular, fisiología, así como para médicos, fisioterapeutas en cardiología, medicina deportiva, etc. Nota de contenido: Part I: Overview -- Chapter 1: Physical inactivity and the economic and health burdens due to cardiovascular disease: exercise as medicine (Mark Hamer) -- Part II: Cardiac Exercise Physiology -- Chapter 2: Acute and chronic response to exercise in athletes: the "Supernormal Heart (Antonello D'Andrea) -- Chapter 3: The effects of exercise on cardiovascular biomarkers: new insights, recent data, and applications (Lin Che) -- Chapter 4: Acute and chronic exercise in animal models (Vu Thi Thu) -- Part III: Cardiac Cells Adaptations in Exercise -- Chapter 5 Structural, contractile and electrophysiological adaptations of cardiomyocytes to chronic exercise (Krzesiak A) -- Chapter 6: Formation of new cardiomyocytes in exercise (Liang Shen) -- Chapter 7: Physical exercise can spur beneficial neoangiogenesis and microvasculature remodeling within the heart - our salvation? (Michal Miko) -- Chapter 8 The non-cardiomyocyte cells of heart. their possible roles in exercise-based cardiac regeneration, reparation and remodeling (Ivan Varga) -- Part IV: Exercise benefits the Heart: Basic Science Evidence -- Chapter 9: Myocardial infarction and exercise training: evidence from basic science (Ivana Cinthya Moraes-Silva) -- Chapter 10: Cardiac ischemia/reperfusion injury (Juliana Pereira Borges) -- Chapter 11: Experimental evidences supporting the benefits of exercise training in heart failure (Marcelo H. A. Ichige) -- Chapter 12: Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: possible underlying mechanisms (Ayman M. Mahmoud) -- Chapter 13: Cardiac aging – benefits of exercise, Nrf2 activation and antioxidant signaling (Madhusudhanan Narasimhan) -- Chapter 14: Cardiac fibrosis:the beneficial effects of exercise in cardiac fibrosis (Jan Kyselovič) -- Chapter 15: Physical exercise is a potential "medicine" for atherosclerosis (Jian Yang) -- Chapter 16: Experimental evidences supporting training-induced benefits in spontaneously hypertensive rats (GustavoS. Masson) -- Chapter 17: Exercise training in pulmonary hypertension and right heart failure: insights from pre-clinical studies (Daniel Moreira-Gonçalves) -- Part V: Exercise benefits the Heart: Clinical Evidence -- Chapter 18: Coronary heart disease (Lei Wang) -- Chapter 19: Exercise exerts its beneficial effects on acute coronary syndrome：clinical evidence (Zhuyuan Liu) -- Chapter 20: Exercise-based rehabilitation for heart failure:clinical evidence (Rongjing Ding) -- Chapter 21: The benefits of exercise training on aerobic capacity in patients with Heart Failure and Preserved Ejection Fraction (Danilo Marcelo Leite do Prado) -- Chapter 22: Hypertension and exercise training: evidence from clinical studies (Ivana Cinthya Moraes-Silva) -- Chapter 23: Effects of exercise on arrhythmia (and viceversa): lesson from the Greek mythology (Caterina Lambiase) -- Chapter 24: Exercise and congenital heart disease (Junnan Wang) -- Chapter 25: The Positive Effects of Exercise in Chemotherapy-related Cardiomyopathy (Cavarretta Elena) -- Chapter 26: Clinical evidence of exercise benefits for stroke (Peipei Han) -- Chapter 27: Pulmonary hypertension (Abraham Samuel Babu) -- Chapter 28: Peripheral vascular disease (Basant Elnady) -- Part VI: Molecular Mechanisms -- Chapter 29 Molecular mechanisms (Kate L. Weeks) -- Chapter 30: NO Signaling in the cardiovascular system and exercise (Tiago Fernandes) -- Chapter 31: C/EBPB-CITED4 in exercised heart (Shengguang Ding) -- Chapter 32: MicroRNAs mediate beneficial effects of exercise in heart (Yihua Bei) -- Chapter 33: Exercise training and epigenetic regulation: multilevel modification and regulation of gene expression (Ursula Paula Renó Soci) -- Chapter 34: Exercise-induced mitochondrial adaptations in addressing heart failure (Jubert Marquez) -- Chapter 35: Exosomes mediate the beneficial effects of exercise (Yangxin Li) -- Part VII: Exercise Dosing and Prescription -- Chapter 36: Exercise dosing and prescription-Playing it safe: dangers and prescription(Lei Wang). Tipo de medio : Computadora Summary : The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Exercise for Cardiovascular Disease Prevention and Treatment : From Molecular to Clinical, Part 2 [documento electrónico] / Xiao, Junjie, . - 1 ed. . - Singapore [Malasia] : Springer, 2017 . - VII, 387 p. 39 ilustraciones, 33 ilustraciones en color.
ISBN : 978-981-10-4304-8
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Fisiología humana Biología Cardiología Investigación biomédica Clasificación: 612 Medicina (Fisiología humana) Resumen: El libro ofrece una visión general intensiva sobre el ejercicio para la prevención y el tratamiento de enfermedades cardiovasculares, desde la investigación básica hasta la práctica clínica. En primer lugar, el volumen resume la respuesta aguda y crónica al ejercicio. En segundo lugar, se resume la evidencia sobre el ejercicio como medicina para el corazón basada en estudios clínicos e investigaciones básicas. En tercer lugar, se presentan los mecanismos moleculares que median los efectos beneficiosos del ejercicio, incluida la señalización IGF-1-PI3K-AKT, la señalización NO, la señalización C/EBPB-Cited4, los ARN no codificantes, los reguladores epigenéticos, la adaptación de las mitocondrias y los exosomas. Finalmente, se proporcionan la dosis, la prescripción y las perspectivas futuras del ejercicio. Este libro proporcionará una valiosa referencia para investigadores en biología celular, fisiología, así como para médicos, fisioterapeutas en cardiología, medicina deportiva, etc. Nota de contenido: Part I: Overview -- Chapter 1: Physical inactivity and the economic and health burdens due to cardiovascular disease: exercise as medicine (Mark Hamer) -- Part II: Cardiac Exercise Physiology -- Chapter 2: Acute and chronic response to exercise in athletes: the "Supernormal Heart (Antonello D'Andrea) -- Chapter 3: The effects of exercise on cardiovascular biomarkers: new insights, recent data, and applications (Lin Che) -- Chapter 4: Acute and chronic exercise in animal models (Vu Thi Thu) -- Part III: Cardiac Cells Adaptations in Exercise -- Chapter 5 Structural, contractile and electrophysiological adaptations of cardiomyocytes to chronic exercise (Krzesiak A) -- Chapter 6: Formation of new cardiomyocytes in exercise (Liang Shen) -- Chapter 7: Physical exercise can spur beneficial neoangiogenesis and microvasculature remodeling within the heart - our salvation? (Michal Miko) -- Chapter 8 The non-cardiomyocyte cells of heart. their possible roles in exercise-based cardiac regeneration, reparation and remodeling (Ivan Varga) -- Part IV: Exercise benefits the Heart: Basic Science Evidence -- Chapter 9: Myocardial infarction and exercise training: evidence from basic science (Ivana Cinthya Moraes-Silva) -- Chapter 10: Cardiac ischemia/reperfusion injury (Juliana Pereira Borges) -- Chapter 11: Experimental evidences supporting the benefits of exercise training in heart failure (Marcelo H. A. Ichige) -- Chapter 12: Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: possible underlying mechanisms (Ayman M. Mahmoud) -- Chapter 13: Cardiac aging – benefits of exercise, Nrf2 activation and antioxidant signaling (Madhusudhanan Narasimhan) -- Chapter 14: Cardiac fibrosis:the beneficial effects of exercise in cardiac fibrosis (Jan Kyselovič) -- Chapter 15: Physical exercise is a potential "medicine" for atherosclerosis (Jian Yang) -- Chapter 16: Experimental evidences supporting training-induced benefits in spontaneously hypertensive rats (GustavoS. Masson) -- Chapter 17: Exercise training in pulmonary hypertension and right heart failure: insights from pre-clinical studies (Daniel Moreira-Gonçalves) -- Part V: Exercise benefits the Heart: Clinical Evidence -- Chapter 18: Coronary heart disease (Lei Wang) -- Chapter 19: Exercise exerts its beneficial effects on acute coronary syndrome：clinical evidence (Zhuyuan Liu) -- Chapter 20: Exercise-based rehabilitation for heart failure:clinical evidence (Rongjing Ding) -- Chapter 21: The benefits of exercise training on aerobic capacity in patients with Heart Failure and Preserved Ejection Fraction (Danilo Marcelo Leite do Prado) -- Chapter 22: Hypertension and exercise training: evidence from clinical studies (Ivana Cinthya Moraes-Silva) -- Chapter 23: Effects of exercise on arrhythmia (and viceversa): lesson from the Greek mythology (Caterina Lambiase) -- Chapter 24: Exercise and congenital heart disease (Junnan Wang) -- Chapter 25: The Positive Effects of Exercise in Chemotherapy-related Cardiomyopathy (Cavarretta Elena) -- Chapter 26: Clinical evidence of exercise benefits for stroke (Peipei Han) -- Chapter 27: Pulmonary hypertension (Abraham Samuel Babu) -- Chapter 28: Peripheral vascular disease (Basant Elnady) -- Part VI: Molecular Mechanisms -- Chapter 29 Molecular mechanisms (Kate L. Weeks) -- Chapter 30: NO Signaling in the cardiovascular system and exercise (Tiago Fernandes) -- Chapter 31: C/EBPB-CITED4 in exercised heart (Shengguang Ding) -- Chapter 32: MicroRNAs mediate beneficial effects of exercise in heart (Yihua Bei) -- Chapter 33: Exercise training and epigenetic regulation: multilevel modification and regulation of gene expression (Ursula Paula Renó Soci) -- Chapter 34: Exercise-induced mitochondrial adaptations in addressing heart failure (Jubert Marquez) -- Chapter 35: Exosomes mediate the beneficial effects of exercise (Yangxin Li) -- Part VII: Exercise Dosing and Prescription -- Chapter 36: Exercise dosing and prescription-Playing it safe: dangers and prescription(Lei Wang). Tipo de medio : Computadora Summary : The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
Título : Exosomes in Cardiovascular Diseases : Biomarkers, Pathological and Therapeutic Effects Tipo de documento: documento electrónico Autores: Xiao, Junjie, ; Cretoiu, Sanda, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2017 Número de páginas: VII, 307 p. 32 ilustraciones, 30 ilustraciones en color. ISBN/ISSN/DL: 978-981-10-4397-0 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Biología Fisiología humana Cardiología Investigación biomédica Clasificación: 610.72 Resumen: El libro proporciona una visión general intensiva sobre los exosomas en las enfermedades cardiovasculares, su potencial como biomarcadores, así como sus efectos patológicos y terapéuticos. En primer lugar, describe los aspectos generales de los exosomas, incluida la definición, formación y secreción de exosomas, y también destaca sus funciones como biomarcadores y efectos patológicos y terapéuticos en enfermedades cardiovasculares. En segundo lugar, se resumen los aspectos básicos de los exosomas, incluidos los métodos de purificación de los exosomas, el contenido de los exosomas y las funciones funcionales de los exosomas cardiovasculares. En tercer lugar, se analizan los exosomas como biomarcadores de enfermedades cardiovasculares, incluido su papel en el diagnóstico, el pronóstico y la reacción al tratamiento. En cuarto lugar, se destacan los efectos patológicos de los exosomas y los efectos terapéuticos de los exosomas. Por último, se proporcionarían perspectivas futuras de los exosomas en la investigación cardiovascular. Se trata de una referencia imprescindible para los investigadores que trabajan en biología y regeneración celular, así como para médicos como los cardiólogos. Nota de contenido: Section 1. Overview -- Section 2. Basic aspects of exosomes. -- Section 3. Exosomes as biomarkers of cardiovascular diseases. -- Section 4. Pathological Effects of Exosomes. -- Section 5. Therapeutic effects of Exosomes. -- Section 6. Future Prospects. Tipo de medio : Computadora Summary : The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Exosomes in Cardiovascular Diseases : Biomarkers, Pathological and Therapeutic Effects [documento electrónico] / Xiao, Junjie, ; Cretoiu, Sanda, . - 1 ed. . - Singapore [Malasia] : Springer, 2017 . - VII, 307 p. 32 ilustraciones, 30 ilustraciones en color.
ISBN : 978-981-10-4397-0
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Biología Fisiología humana Cardiología Investigación biomédica Clasificación: 610.72 Resumen: El libro proporciona una visión general intensiva sobre los exosomas en las enfermedades cardiovasculares, su potencial como biomarcadores, así como sus efectos patológicos y terapéuticos. En primer lugar, describe los aspectos generales de los exosomas, incluida la definición, formación y secreción de exosomas, y también destaca sus funciones como biomarcadores y efectos patológicos y terapéuticos en enfermedades cardiovasculares. En segundo lugar, se resumen los aspectos básicos de los exosomas, incluidos los métodos de purificación de los exosomas, el contenido de los exosomas y las funciones funcionales de los exosomas cardiovasculares. En tercer lugar, se analizan los exosomas como biomarcadores de enfermedades cardiovasculares, incluido su papel en el diagnóstico, el pronóstico y la reacción al tratamiento. En cuarto lugar, se destacan los efectos patológicos de los exosomas y los efectos terapéuticos de los exosomas. Por último, se proporcionarían perspectivas futuras de los exosomas en la investigación cardiovascular. Se trata de una referencia imprescindible para los investigadores que trabajan en biología y regeneración celular, así como para médicos como los cardiólogos. Nota de contenido: Section 1. Overview -- Section 2. Basic aspects of exosomes. -- Section 3. Exosomes as biomarkers of cardiovascular diseases. -- Section 4. Pathological Effects of Exosomes. -- Section 5. Therapeutic effects of Exosomes. -- Section 6. Future Prospects. Tipo de medio : Computadora Summary : The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
Título : Muscle Atrophy Tipo de documento: documento electrónico Autores: Xiao, Junjie, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2018 Número de páginas: XV, 624 p. 76 ilustraciones, 52 ilustraciones en color. ISBN/ISSN/DL: 978-981-1314353-- Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Biología Citología Fisiología humana Investigación biomédica Biología Celular Clasificación: 610.72 Resumen: El libro aborda el desarrollo de la atrofia muscular, que puede ser causada por denervación, desuso, ayuno excesivo, envejecimiento y una variedad de enfermedades que incluyen insuficiencia cardíaca, enfermedades renales crónicas y cánceres. La atrofia muscular reduce la calidad de vida y aumenta la morbilidad y la mortalidad en todo el mundo. El libro se divide en cinco partes, la primera de las cuales describe los aspectos generales de la atrofia muscular, incluidas sus características, las cargas económicas y de salud relacionadas y la terapia clínica actual. En segundo lugar, se resumen los aspectos básicos de la atrofia muscular, incluida la composición, estructura y función del músculo esquelético, los cambios musculares en respuesta a la atrofia y los modelos experimentales. En tercer lugar, el libro revisa los mecanismos moleculares de la atrofia muscular, incluidas las vías de síntesis y degradación de proteínas, los ARN no codificantes, la señalización inflamatoria, el estrés oxidativo, la señalización mitocondrial, etc. En cuarto lugar, destaca los mecanismos fisiopatológicos de la atrofia muscular en el envejecimiento y las enfermedades. La quinta y última parte del libro cubre el diagnóstico, las estrategias de tratamiento, los agentes prometedores y las perspectivas futuras de la atrofia muscular. El libro atraerá a un amplio público de lectores, incluidos científicos, estudiantes de pregrado y posgrado en medicina y biología celular. Nota de contenido: An overview of muscle atrophy -- Myofibers -- Muscle mass, quality, and composition changes during atrophy and sarcopenia -- Muscle changes during atrophy -- Skeleton muscle damage in intorauterine growth restriction -- The role of IGF-1 signaling in skeletal muscle atrophy -- mTOR signaling pathway and protein synthesis: from training to aging and muscle autophagy -- Past, present and future perspective of targeting myostatin and related signaling pathways to counteract muscle atrophy -- Hormones and muscle atrophy -- Ubiquitin-proteasome pathway and muscle atrophy -- Noncoding RNAs in muscle atrophy -- NF-kB and inflammatory cytokine signalling; role in skeletal muscle atrophy -- Redox homeostasis in age-related muscle atrophy -- Disturbed Ca2+ homeostasis in muscle wasting disorders -- Muscle atrophy in cancer -- The molecular mechanisms and prevention principles of muscle atrophy in aging -- Muscle atrophy in cardiovascular diseases -- Muscle atrophy in chronic kidney diseases -- Sarcopenia in liver disease: current evidence and issues to be resolved -- Muscle atrophy measurement as assessment method for low back pain patients -- Drugs of muscle wasting and their therapeutic targets -- Nutritional support to counteract muscle atrophy -- Nutritional considerations in preventing muscle atrophy -- Physical exercise for muscle atrophy -- To contrast and reverse skeletal muscle atrophy by Full-Body In-Bed Gym, a mandatory life-style for older olds and borderline mobility impaired persons -- Overview of FES-assisted cycling approaches and their benefits on functional rehabilitation and muscle atrophy -- The reversal of atrophy in human skeletal muscles by home-based Functional Electrical Stimulation after complete SCI lower motor neuron denervation -- Preverting muscle atrophy following strokes- a reappraisal -- Muscle atrophy: present and future. Tipo de medio : Computadora Summary : The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book's fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Muscle Atrophy [documento electrónico] / Xiao, Junjie, . - 1 ed. . - Singapore [Malasia] : Springer, 2018 . - XV, 624 p. 76 ilustraciones, 52 ilustraciones en color.
ISBN : 978-981-1314353--
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Biología Citología Fisiología humana Investigación biomédica Biología Celular Clasificación: 610.72 Resumen: El libro aborda el desarrollo de la atrofia muscular, que puede ser causada por denervación, desuso, ayuno excesivo, envejecimiento y una variedad de enfermedades que incluyen insuficiencia cardíaca, enfermedades renales crónicas y cánceres. La atrofia muscular reduce la calidad de vida y aumenta la morbilidad y la mortalidad en todo el mundo. El libro se divide en cinco partes, la primera de las cuales describe los aspectos generales de la atrofia muscular, incluidas sus características, las cargas económicas y de salud relacionadas y la terapia clínica actual. En segundo lugar, se resumen los aspectos básicos de la atrofia muscular, incluida la composición, estructura y función del músculo esquelético, los cambios musculares en respuesta a la atrofia y los modelos experimentales. En tercer lugar, el libro revisa los mecanismos moleculares de la atrofia muscular, incluidas las vías de síntesis y degradación de proteínas, los ARN no codificantes, la señalización inflamatoria, el estrés oxidativo, la señalización mitocondrial, etc. En cuarto lugar, destaca los mecanismos fisiopatológicos de la atrofia muscular en el envejecimiento y las enfermedades. La quinta y última parte del libro cubre el diagnóstico, las estrategias de tratamiento, los agentes prometedores y las perspectivas futuras de la atrofia muscular. El libro atraerá a un amplio público de lectores, incluidos científicos, estudiantes de pregrado y posgrado en medicina y biología celular. Nota de contenido: An overview of muscle atrophy -- Myofibers -- Muscle mass, quality, and composition changes during atrophy and sarcopenia -- Muscle changes during atrophy -- Skeleton muscle damage in intorauterine growth restriction -- The role of IGF-1 signaling in skeletal muscle atrophy -- mTOR signaling pathway and protein synthesis: from training to aging and muscle autophagy -- Past, present and future perspective of targeting myostatin and related signaling pathways to counteract muscle atrophy -- Hormones and muscle atrophy -- Ubiquitin-proteasome pathway and muscle atrophy -- Noncoding RNAs in muscle atrophy -- NF-kB and inflammatory cytokine signalling; role in skeletal muscle atrophy -- Redox homeostasis in age-related muscle atrophy -- Disturbed Ca2+ homeostasis in muscle wasting disorders -- Muscle atrophy in cancer -- The molecular mechanisms and prevention principles of muscle atrophy in aging -- Muscle atrophy in cardiovascular diseases -- Muscle atrophy in chronic kidney diseases -- Sarcopenia in liver disease: current evidence and issues to be resolved -- Muscle atrophy measurement as assessment method for low back pain patients -- Drugs of muscle wasting and their therapeutic targets -- Nutritional support to counteract muscle atrophy -- Nutritional considerations in preventing muscle atrophy -- Physical exercise for muscle atrophy -- To contrast and reverse skeletal muscle atrophy by Full-Body In-Bed Gym, a mandatory life-style for older olds and borderline mobility impaired persons -- Overview of FES-assisted cycling approaches and their benefits on functional rehabilitation and muscle atrophy -- The reversal of atrophy in human skeletal muscles by home-based Functional Electrical Stimulation after complete SCI lower motor neuron denervation -- Preverting muscle atrophy following strokes- a reappraisal -- Muscle atrophy: present and future. Tipo de medio : Computadora Summary : The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book's fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
