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Autor Guest, Paul C. |
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TÃtulo : Biomarkers and Mental Illness : It's Not All in the Mind Tipo de documento: documento electrónico Autores: Guest, Paul C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2017 Número de páginas: XII, 203 p. 61 ilustraciones, 51 ilustraciones en color. ISBN/ISSN/DL: 978-3-319-46088-8 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Bioinformática Genética Médica PsiquiatrÃa Clasificación: 570.285 Resumen: Empleando un lenguaje accesible en todo momento, este libro cubre la historia de la investigación psiquiátrica, el estado actual de la práctica psiquiátrica, los sistemas fisiológicos afectados por las enfermedades psiquiátricas, la naturaleza integral de estas enfermedades y el impacto que este aspecto tiene en la salud. descubrimientos emergentes de biomarcadores. Además, proporciona descripciones de los principales trastornos psiquiátricos especÃficos y los desafÃos especiales relacionados con el diagnóstico y tratamiento de cada uno. El libro concluye con información sobre los últimos avances en dispositivos portátiles de prueba de biomarcadores, que pueden proporcionar información de diagnóstico en menos de 15 minutos en entornos de punto de atención. Este libro investiga el uso emergente de biomarcadores en el estudio de enfermedades psiquiátricas, un tema de considerable importancia para una amplia gama de personas, incluidos investigadores, médicos, psiquiatras, estudiantes universitarios e incluso aquellos cuyas vidas se ven afectadas de alguna manera por una enfermedad psiquiátrica. La última categorÃa no es trivial, ya que sorprendentemente una de cada tres personas en todo el mundo presenta los criterios de al menos un trastorno psiquiátrico en algún momento de su vida. . Nota de contenido: Part I -- CHAPTER 1 – Psychiatric disorders as "whole body" diseases -- CHAPTER 2 – Treatment of psychiatric disorders: time for a paradigm change? -- CHAPTER 3 – The importance of biomarkers: the required tools of the trade -- Part II -- CHAPTER 4 – Schizophrenia and the mind-body connection -- CHAPTER 5 – Progress for better treatment of depression -- CHAPTER 6 - The special case of bipolar disorder -- CHAPTER 7 – The worrying case of anxiety and stress-related disorders -- CHAPTER 8 - The autism spectrum conditions and the extreme male brain syndrome -- CHAPTER 9 – Gender and psychiatric disorders -- Part III -- CHAPTER 10 – CHAPTER 10 - Biomarkers and new treatments for Alzheimer's disease -- CHAPTER 11 – Parkinson's disease, biomarkers and beyond -- Part IV -- CHAPTER 12 – The future: towards personalized medicine. Tipo de medio : Computadora Summary : Employing accessible language throughout, this book covers the history of psychiatric research, the current state-of-the art in psychiatric practice, the physiological systems affected by psychiatric illnesses, the whole-body nature of these diseases and the impact that this aspect has on emerging biomarker discoveries. Further, it provides descriptions of the major specific psychiatric disorders and the special challenges regarding the diagnosis and treatment of each. The book concludes with insights into the latest developments in hand-held biomarker test devices, which can provide diagnostic information in less than 15 minutes in point-of-care settings. This book investigates the emerging use of biomarkers in the study of psychiatric diseases, a topic of considerable importance for a broad range of people including researchers, clinicians, psychiatrists, university students and even those whose lives are affected in some way by a psychiatric illness. The last category is hardly trivial, since a staggering one in three people worldwide show the criteria for at least one psychiatric disorder at some point in their lifetime. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Biomarkers and Mental Illness : It's Not All in the Mind [documento electrónico] / Guest, Paul C., . - 1 ed. . - [s.l.] : Springer, 2017 . - XII, 203 p. 61 ilustraciones, 51 ilustraciones en color.
ISBN : 978-3-319-46088-8
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: Bioinformática Genética Médica PsiquiatrÃa Clasificación: 570.285 Resumen: Empleando un lenguaje accesible en todo momento, este libro cubre la historia de la investigación psiquiátrica, el estado actual de la práctica psiquiátrica, los sistemas fisiológicos afectados por las enfermedades psiquiátricas, la naturaleza integral de estas enfermedades y el impacto que este aspecto tiene en la salud. descubrimientos emergentes de biomarcadores. Además, proporciona descripciones de los principales trastornos psiquiátricos especÃficos y los desafÃos especiales relacionados con el diagnóstico y tratamiento de cada uno. El libro concluye con información sobre los últimos avances en dispositivos portátiles de prueba de biomarcadores, que pueden proporcionar información de diagnóstico en menos de 15 minutos en entornos de punto de atención. Este libro investiga el uso emergente de biomarcadores en el estudio de enfermedades psiquiátricas, un tema de considerable importancia para una amplia gama de personas, incluidos investigadores, médicos, psiquiatras, estudiantes universitarios e incluso aquellos cuyas vidas se ven afectadas de alguna manera por una enfermedad psiquiátrica. La última categorÃa no es trivial, ya que sorprendentemente una de cada tres personas en todo el mundo presenta los criterios de al menos un trastorno psiquiátrico en algún momento de su vida. . Nota de contenido: Part I -- CHAPTER 1 – Psychiatric disorders as "whole body" diseases -- CHAPTER 2 – Treatment of psychiatric disorders: time for a paradigm change? -- CHAPTER 3 – The importance of biomarkers: the required tools of the trade -- Part II -- CHAPTER 4 – Schizophrenia and the mind-body connection -- CHAPTER 5 – Progress for better treatment of depression -- CHAPTER 6 - The special case of bipolar disorder -- CHAPTER 7 – The worrying case of anxiety and stress-related disorders -- CHAPTER 8 - The autism spectrum conditions and the extreme male brain syndrome -- CHAPTER 9 – Gender and psychiatric disorders -- Part III -- CHAPTER 10 – CHAPTER 10 - Biomarkers and new treatments for Alzheimer's disease -- CHAPTER 11 – Parkinson's disease, biomarkers and beyond -- Part IV -- CHAPTER 12 – The future: towards personalized medicine. Tipo de medio : Computadora Summary : Employing accessible language throughout, this book covers the history of psychiatric research, the current state-of-the art in psychiatric practice, the physiological systems affected by psychiatric illnesses, the whole-body nature of these diseases and the impact that this aspect has on emerging biomarker discoveries. Further, it provides descriptions of the major specific psychiatric disorders and the special challenges regarding the diagnosis and treatment of each. The book concludes with insights into the latest developments in hand-held biomarker test devices, which can provide diagnostic information in less than 15 minutes in point-of-care settings. This book investigates the emerging use of biomarkers in the study of psychiatric diseases, a topic of considerable importance for a broad range of people including researchers, clinicians, psychiatrists, university students and even those whose lives are affected in some way by a psychiatric illness. The last category is hardly trivial, since a staggering one in three people worldwide show the criteria for at least one psychiatric disorder at some point in their lifetime. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
TÃtulo : Clinical, Biological and Molecular Aspects of COVID-19 Tipo de documento: documento electrónico Autores: Guest, Paul C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2021 Número de páginas: XVII, 353 p. 53 ilustraciones, 37 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-59261-5 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: VirologÃa Órganos respiratorios FisiologÃa Metabolismo FisiologÃa respiratoria Clasificación: 579.2 Resumen: El nuevo coronavirus 2019 (COVID-19) ha provocado una grave pandemia mundial en apenas ocho meses. Casi todos los paÃses y territorios del mundo se han visto afectados por el virus. La virulencia y la tasa de infección del virus son profundas y han requerido medidas extremas de distanciamiento social en todo el mundo para evitar que los servicios de salud y los hospitales se abrumen. El COVID-19 parece tener mayores efectos en las personas de edad avanzada y en quienes padecen enfermedades comórbidas, como enfermedades cardÃacas, asma y diabetes. A medida que el pico comienza a disminuir en muchos paÃses, las tasas de mortalidad siguen siendo altas en medio de temores justificados de una segunda ola. Ha comenzado una rápida movilización mundial para identificar tratamientos eficaces y desarrollar vacunas. Este nuevo volumen aumentará la comprensión de los lectores sobre la actual pandemia de COVID-19 a través de una serie de capÃtulos que abordan estas preocupaciones. Los principales expertos discutirán los efectos del virus en casos de comorbilidades, nuevos enfoques de tratamiento, aspectos de salud mental de la pandemia y transmitirán los resultados de las encuestas. El libro será un excelente recurso para investigadores que estudian virologÃa, enfermedades metabólicas, trastornos respiratorios y cientÃficos clÃnicos, médicos, compañÃas farmacéuticas y trabajadores y servicios de atención médica. Nota de contenido: SARS-CoV-2 (COVID-19): Beginning to Understand a New Virus -- Neurological Complications of the COVID-19 Pandemic: What have we got so Far? -- Endothelial Dysfunction as a Primary Consequence of SARS-CoV-2 Infection -- A Review Study on the Neonatal Outcomes of Pregnant Women with COVID-19 -- Relationship between COVID-19 and Angiotensin-Converting Enzyme 2: A Scoping Review -- Experience in Nutrition Management of Diabetes-affected COVID-19 Patients -- Emerging Technologies for the Treatment of COVID-19 -- Obesity and risk of COVID-19 infection and severity: available evidence and mechanisms -- COVID-19 is an Endothelial Disease: Implications of Nitric Oxide -- Immune Response and Effectiveness of COVID-19 Therapies -- The Novel Coronavirus and Inflammation -- Does SARS-CoV-2 Threaten Male Fertility? -- COVID-19 and Vulnerable Populations in Sub-Saharan Africa: a Review -- Overview of the Haematological Effects of COVID-19 Infection -- The Novel Coronavirus and Haemostatic Abnormalities: Pathophysiology, Clinical Manifestations and Treatment Recommendations -- COVID-19 related laboratory analyte changes and the relationship between SARS-CoV-2 and HIV, TB and HbA1c in South Africa -- The Primary Outcomes, Epidemiological and Clinical Features of Coronavirus Disease-2019 (COVID-19) in Iran -- Acute Respiratory Distress Syndrome and COVID-19: A Scoping Review and Meta-Analysis -- Depression, Anxiety and Stress Among Patients with COVID-19: A Cross-sectional Study -- Survey of Immediate Psychological Distress Levels among Health Care Workers in the COVID-19 Epidemic: A Cross-sectional Study -- Coronavirus (COVID-19)-Associated Psychological Distress Among Medical Students in Iran -- A Survey of Psychological Distress among the Community in the COVID-19 Epidemic: A Cross-Sectional Study -- Gender Susceptibility to COVID-19 Mortality: Androgens as the Usual Suspects? -- Identification, Monitoring and Prediction of Disease Severity in Patients with COVID-19 Pneumonia Based on Chest Computed Tomography Scans: a Retrospective Study -- The Level of Procalcitonin in Severe COVID-19 Patients: A Systematic Review and Meta-analysis -- A Systematic Review of 571 Pregnancies Affected by COVID-19 -- The 2019 Novel Coronavirus Disease in Pregnancy: A Systematic Review -- Acute Kidney Injury and Covid-19: a Scoping Review and Meta-analysis -- Cardiac Injury in COVID-19: A Systematic Review -- A Systematic Review of the Assessment of the Presence of SARS-CoV-2 in Human Semen -- Index. Tipo de medio : Computadora Summary : The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Clinical, Biological and Molecular Aspects of COVID-19 [documento electrónico] / Guest, Paul C., . - 1 ed. . - [s.l.] : Springer, 2021 . - XVII, 353 p. 53 ilustraciones, 37 ilustraciones en color.
ISBN : 978-3-030-59261-5
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: VirologÃa Órganos respiratorios FisiologÃa Metabolismo FisiologÃa respiratoria Clasificación: 579.2 Resumen: El nuevo coronavirus 2019 (COVID-19) ha provocado una grave pandemia mundial en apenas ocho meses. Casi todos los paÃses y territorios del mundo se han visto afectados por el virus. La virulencia y la tasa de infección del virus son profundas y han requerido medidas extremas de distanciamiento social en todo el mundo para evitar que los servicios de salud y los hospitales se abrumen. El COVID-19 parece tener mayores efectos en las personas de edad avanzada y en quienes padecen enfermedades comórbidas, como enfermedades cardÃacas, asma y diabetes. A medida que el pico comienza a disminuir en muchos paÃses, las tasas de mortalidad siguen siendo altas en medio de temores justificados de una segunda ola. Ha comenzado una rápida movilización mundial para identificar tratamientos eficaces y desarrollar vacunas. Este nuevo volumen aumentará la comprensión de los lectores sobre la actual pandemia de COVID-19 a través de una serie de capÃtulos que abordan estas preocupaciones. Los principales expertos discutirán los efectos del virus en casos de comorbilidades, nuevos enfoques de tratamiento, aspectos de salud mental de la pandemia y transmitirán los resultados de las encuestas. El libro será un excelente recurso para investigadores que estudian virologÃa, enfermedades metabólicas, trastornos respiratorios y cientÃficos clÃnicos, médicos, compañÃas farmacéuticas y trabajadores y servicios de atención médica. Nota de contenido: SARS-CoV-2 (COVID-19): Beginning to Understand a New Virus -- Neurological Complications of the COVID-19 Pandemic: What have we got so Far? -- Endothelial Dysfunction as a Primary Consequence of SARS-CoV-2 Infection -- A Review Study on the Neonatal Outcomes of Pregnant Women with COVID-19 -- Relationship between COVID-19 and Angiotensin-Converting Enzyme 2: A Scoping Review -- Experience in Nutrition Management of Diabetes-affected COVID-19 Patients -- Emerging Technologies for the Treatment of COVID-19 -- Obesity and risk of COVID-19 infection and severity: available evidence and mechanisms -- COVID-19 is an Endothelial Disease: Implications of Nitric Oxide -- Immune Response and Effectiveness of COVID-19 Therapies -- The Novel Coronavirus and Inflammation -- Does SARS-CoV-2 Threaten Male Fertility? -- COVID-19 and Vulnerable Populations in Sub-Saharan Africa: a Review -- Overview of the Haematological Effects of COVID-19 Infection -- The Novel Coronavirus and Haemostatic Abnormalities: Pathophysiology, Clinical Manifestations and Treatment Recommendations -- COVID-19 related laboratory analyte changes and the relationship between SARS-CoV-2 and HIV, TB and HbA1c in South Africa -- The Primary Outcomes, Epidemiological and Clinical Features of Coronavirus Disease-2019 (COVID-19) in Iran -- Acute Respiratory Distress Syndrome and COVID-19: A Scoping Review and Meta-Analysis -- Depression, Anxiety and Stress Among Patients with COVID-19: A Cross-sectional Study -- Survey of Immediate Psychological Distress Levels among Health Care Workers in the COVID-19 Epidemic: A Cross-sectional Study -- Coronavirus (COVID-19)-Associated Psychological Distress Among Medical Students in Iran -- A Survey of Psychological Distress among the Community in the COVID-19 Epidemic: A Cross-Sectional Study -- Gender Susceptibility to COVID-19 Mortality: Androgens as the Usual Suspects? -- Identification, Monitoring and Prediction of Disease Severity in Patients with COVID-19 Pneumonia Based on Chest Computed Tomography Scans: a Retrospective Study -- The Level of Procalcitonin in Severe COVID-19 Patients: A Systematic Review and Meta-analysis -- A Systematic Review of 571 Pregnancies Affected by COVID-19 -- The 2019 Novel Coronavirus Disease in Pregnancy: A Systematic Review -- Acute Kidney Injury and Covid-19: a Scoping Review and Meta-analysis -- Cardiac Injury in COVID-19: A Systematic Review -- A Systematic Review of the Assessment of the Presence of SARS-CoV-2 in Human Semen -- Index. Tipo de medio : Computadora Summary : The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
TÃtulo : Identification of Biomarkers, New Treatments, and Vaccines for COVID-19 Tipo de documento: documento electrónico Autores: Guest, Paul C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2021 Número de páginas: IX, 234 p. 28 ilustraciones, 24 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-71697-4 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: VirologÃa Marcadores bioquÃmicos Órganos respiratorios FisiologÃa Biomarcadores FisiologÃa respiratoria Clasificación: 579.2 Resumen: El nuevo coronavirus 2019 (COVID-19) ha provocado una grave pandemia mundial en tan solo un año. Casi todos los paÃses y territorios del mundo se han visto afectados por el virus. La virulencia y la tasa de infección del virus son profundas y han requerido medidas extremas de distanciamiento social en todo el mundo para evitar que los servicios de salud y los hospitales se abrumen. La COVID-19 parece tener mayores efectos en las personas de edad avanzada y en quienes padecen enfermedades comórbidas, como diabetes y obesidad. Dado que los casos y la tasa de mortalidad siguen siendo altos, existen temores justificados de que este virus permanezca durante varios meses o años. Para abordar esto, ha comenzado un esfuerzo de movilización mundial rápido y sin precedentes para identificar tratamientos eficaces y desarrollar vacunas. A medida que estos comienzan a implementarse y administrarse en todo el mundo, muchos sienten que el virus estará bajo control y que la vida eventualmente volverá a la normalidad. Este nuevo volumen aumentará la comprensión de los lectores sobre la actual pandemia de COVID-19 a través de una serie de capÃtulos que abordan estas preocupaciones. Los principales expertos discutirán nuevos enfoques de tratamiento, el desarrollo de vacunas, los aspectos de salud mental de la pandemia y transmitirán los resultados de los estudios de encuesta. El libro será un excelente recurso para investigadores que estudian virologÃa, enfermedades metabólicas, trastornos respiratorios y cientÃficos clÃnicos, médicos, compañÃas farmacéuticas y trabajadores y servicios de atención médica. . Nota de contenido: 1. Genetic Aspects and Immune Responses in Covid-19: Important Organ Involvement -- 2. Prevalence of COVID-19 and the Continued Citizen-based Control in Japan -- 3. COVID-19 Pandemicin Brazil: History, Characteristics, and Evolution -- 4. The Experiences of Recovered COVID-19 Patients in Baqiyatallah Hospital: A Qualitative Study -- 5. Age-specific Differences in the Severity of COVID-19 Between Children and Adults: Reality and Reasons -- 6. Sex differences and COVID-19 -- 7. Intestinal Microbiota in the Sars-Cov2 Infection: What is known? -- 8. SARS-CoV-2 Infection and the Kidneys: an Evolving Picture -- 9. Cutaneous Manifestations of COVID-19: Early Diagnosis and Prognostic Information -- 10. How do we Manage Breastfeeding during the COVID-19 Pandemic? -- 11. Deep Learning Analysis in Prediction of COVID-19 Infection Status using Chest CT Scan Features -- 12. Using Ozone Therapy as an Option for Treatment of COVID-19 Patients: A Scoping Review -- 13. COVID-19, Coenzyme Q10 and Selenium -- 14. Topical Oral and Intranasal Antiviral Agents for Coronavirus Disease 2019 (COVID-19) -- 15. Cinnamon: A Promising Natural Product against COVID-19 -- 16. Curcumin and Piperine in COVID-19: a Promising Duo to the Rescue -- 17. Association of in-hospital use of statins, aspirin and renin-angiotensin-aldosterone inhibitors with mortality and ICU admission due to COVID-19A -- 18. The Worldwide Effort to Develop Vaccines for COVID-19. Tipo de medio : Computadora Summary : The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as diabetes and obesity. As the cases and death rate remain high, there are justified fears of this virus remaining for several months or years to come. To address this, a rapid and unprecedented worldwide mobilization effort has begun to identify effective treatments and develop vaccines. As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss new treatment approaches, vaccine development, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Identification of Biomarkers, New Treatments, and Vaccines for COVID-19 [documento electrónico] / Guest, Paul C., . - 1 ed. . - [s.l.] : Springer, 2021 . - IX, 234 p. 28 ilustraciones, 24 ilustraciones en color.
ISBN : 978-3-030-71697-4
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: VirologÃa Marcadores bioquÃmicos Órganos respiratorios FisiologÃa Biomarcadores FisiologÃa respiratoria Clasificación: 579.2 Resumen: El nuevo coronavirus 2019 (COVID-19) ha provocado una grave pandemia mundial en tan solo un año. Casi todos los paÃses y territorios del mundo se han visto afectados por el virus. La virulencia y la tasa de infección del virus son profundas y han requerido medidas extremas de distanciamiento social en todo el mundo para evitar que los servicios de salud y los hospitales se abrumen. La COVID-19 parece tener mayores efectos en las personas de edad avanzada y en quienes padecen enfermedades comórbidas, como diabetes y obesidad. Dado que los casos y la tasa de mortalidad siguen siendo altos, existen temores justificados de que este virus permanezca durante varios meses o años. Para abordar esto, ha comenzado un esfuerzo de movilización mundial rápido y sin precedentes para identificar tratamientos eficaces y desarrollar vacunas. A medida que estos comienzan a implementarse y administrarse en todo el mundo, muchos sienten que el virus estará bajo control y que la vida eventualmente volverá a la normalidad. Este nuevo volumen aumentará la comprensión de los lectores sobre la actual pandemia de COVID-19 a través de una serie de capÃtulos que abordan estas preocupaciones. Los principales expertos discutirán nuevos enfoques de tratamiento, el desarrollo de vacunas, los aspectos de salud mental de la pandemia y transmitirán los resultados de los estudios de encuesta. El libro será un excelente recurso para investigadores que estudian virologÃa, enfermedades metabólicas, trastornos respiratorios y cientÃficos clÃnicos, médicos, compañÃas farmacéuticas y trabajadores y servicios de atención médica. . Nota de contenido: 1. Genetic Aspects and Immune Responses in Covid-19: Important Organ Involvement -- 2. Prevalence of COVID-19 and the Continued Citizen-based Control in Japan -- 3. COVID-19 Pandemicin Brazil: History, Characteristics, and Evolution -- 4. The Experiences of Recovered COVID-19 Patients in Baqiyatallah Hospital: A Qualitative Study -- 5. Age-specific Differences in the Severity of COVID-19 Between Children and Adults: Reality and Reasons -- 6. Sex differences and COVID-19 -- 7. Intestinal Microbiota in the Sars-Cov2 Infection: What is known? -- 8. SARS-CoV-2 Infection and the Kidneys: an Evolving Picture -- 9. Cutaneous Manifestations of COVID-19: Early Diagnosis and Prognostic Information -- 10. How do we Manage Breastfeeding during the COVID-19 Pandemic? -- 11. Deep Learning Analysis in Prediction of COVID-19 Infection Status using Chest CT Scan Features -- 12. Using Ozone Therapy as an Option for Treatment of COVID-19 Patients: A Scoping Review -- 13. COVID-19, Coenzyme Q10 and Selenium -- 14. Topical Oral and Intranasal Antiviral Agents for Coronavirus Disease 2019 (COVID-19) -- 15. Cinnamon: A Promising Natural Product against COVID-19 -- 16. Curcumin and Piperine in COVID-19: a Promising Duo to the Rescue -- 17. Association of in-hospital use of statins, aspirin and renin-angiotensin-aldosterone inhibitors with mortality and ICU admission due to COVID-19A -- 18. The Worldwide Effort to Develop Vaccines for COVID-19. Tipo de medio : Computadora Summary : The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as diabetes and obesity. As the cases and death rate remain high, there are justified fears of this virus remaining for several months or years to come. To address this, a rapid and unprecedented worldwide mobilization effort has begun to identify effective treatments and develop vaccines. As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss new treatment approaches, vaccine development, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
TÃtulo : Proteomic Methods in Neuropsychiatric Research Tipo de documento: documento electrónico Autores: Guest, Paul C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2017 Número de páginas: XII, 370 p. 55 ilustraciones, 45 ilustraciones en color. ISBN/ISSN/DL: 978-3-319-52479-5 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: ProteÃnas Genética molecular Genética Médica BioquÃmica de proteÃnas Genética clÃnica Clasificación: 572.6 Resumen: Debido a los continuos avances técnicos y nuevos conocimientos sobre la alta complejidad de las enfermedades neurológicas, existe una necesidad cada vez mayor de la aplicación de tecnologÃas proteómicas que puedan generar lecturas potenciales de biomarcadores para una mejor gestión clÃnica, asà como para el desarrollo de nuevos medicamentos por parte de las empresas farmacéuticas en dificultades. . Este libro describe el uso paso a paso de métodos proteómicos como la electroforesis en gel bidimensional, el inmunoensayo múltiple, la cromatografÃa lÃquida, la espectrometrÃa de masas (LC-MS) y el monitoreo selectivo de reacciones MS, para aumentar nuestra comprensión de estas enfermedades, con lo último. objetivo de mejorar la atención al paciente. El volumen será de gran interés para cientÃficos clÃnicos, médicos y cientÃficos de compañÃas farmacéuticas, ya que brinda información sobre las últimas tecnologÃas que permiten la revolución de la medicina personalizada. Es de interés directo para los cientÃficos de biomarcadores tanto técnicos como de laboratorio, ya que brinda instrucciones paso a paso sobre cómo llevar a cabo cada uno de los protocolos. También es de interés para los investigadores, ya que cada técnica se presentará en el contexto de un trastorno neurológico especÃfico, incluida la enfermedad de Alzheimer, la esclerosis múltiple, los trastornos del espectro autista, la esquizofrenia, el trastorno depresivo mayor y el trastorno bipolar. Finalmente, también resaltará los futuros esfuerzos de investigación en este campo, que se esfuerzan por convertir las plataformas proteómicas en dispositivos portátiles que puedan usarse en un entorno de atención y devolver resultados de diagnóstico dentro del plazo de una visita al hospital. médico general. Nota de contenido: Preface – Proteomic studies in psychiatric disease and neurological disorders -- Part 1: REVIEWS -- Application of proteomic techniques for improved stratification and treatment of schizophrenia patients -- Multiplexing biomarker methods, proteomics and considerations for Alzheimer's disease -- What have proteomic studies taught us about novel drug targets in autism? -- Application of proteomic approaches to accelerate drug development for psychiatric disorders -- Proteomic biomarker identification in cerebrospinal fluid for leptomeningeal metastases with neurological complications -- Connecting brain proteomics with behavioural neuroscience in translational animal models of neuropsychiatric disorders -- LC-MSE for qualitative and quantitative proteomicstudies of psychiatric disorders -- The utility of multiplex assays for identification of proteomic signatures in psychiatry -- Part 2: PROTOCOLS -- Blood sampling and preparation procedures for proteomic biomarker studies of psychiatric disorders -- Multiplex immunoassay profiling of serum in psychiatric disorders -- Sequential immunopreciptation of secretory vesicle proteins from biosynthetically-labelled cells -- 2d gel electrophoresis of insulin secretory granule proteins from biosynthetically-labelled pancreatic islets -- Two-dimensional gel electrophoresis: a reference protocol -- A two-dimensional difference gel electrophoresis (2D-DIGE) protocol for studies of neural precursor cells -- Identifying biomarker candidates in the blood plasma or serum proteome -- Selective reaction monitoring mass spectrometry for quantitation of glycolytic enzymes in post-mortem brain samples -- A selected reaction monitoring mass spectrometry protocol for validation of proteomic biomarker candidates in studies of psychiatric disorders -- Application of iTRAQ shotgun proteomics for measurement of brain proteins in studies of psychiatric disorders -- Co-immunoprecipitation for deciphering protein interactomes -- Sequential co-immunopreciptation and immunoblot approach to determine oligomerisation of G-protein coupled receptors -- A protocol for producing the maternal low protein rat model: a tool for pre-clinical proteomic studies -- A clinical study protocol to identify serum biomarkers predictive of response to antipsychotics in schizophrenia patients -- Generation of the acute phencyclidine rat model for proteomic studies of schizophrenia A protocol for generation of a corticosterone model of psychiatric disorders -- MK-801-treated oligodendrocytes as a cellular model to study schizophrenia -- Combining patient-reprogrammed neural cells and proteomics as a model to study psychiatric disorders -- SILAC mass spectrometry profiling: a psychiatric disorder perspective -- Preparation of peripheral blood mononuclear cells (PBMCs) as a model for proteomic studies psychiatric disorders -- Proteomic profiling of skin fibroblasts as a model of schizophrenia Proteomic profiling of the pituitary gland in studies of psychiatric disorders -- Development of an assay for measuring proprotein-conversion activity on a multiplex magnetic bead-based array platform -- Phenotyping multiple subsets of immune cells in situ in formalin-fixed, paraffin-embedded tissue sections -- Lab-on-a-chip proteomic assays for psychiatric disorders -- Development of a user-friendly app for testing blood coagulation status in schizophrenia patients -- Part 3:FUTURE PERSPECTIVES -- Proteomic approaches to enable point-of-care testing and personalized medicine for psychiatric disorders. Tipo de medio : Computadora Summary : Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by stepinstructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Proteomic Methods in Neuropsychiatric Research [documento electrónico] / Guest, Paul C., . - 1 ed. . - [s.l.] : Springer, 2017 . - XII, 370 p. 55 ilustraciones, 45 ilustraciones en color.
ISBN : 978-3-319-52479-5
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: ProteÃnas Genética molecular Genética Médica BioquÃmica de proteÃnas Genética clÃnica Clasificación: 572.6 Resumen: Debido a los continuos avances técnicos y nuevos conocimientos sobre la alta complejidad de las enfermedades neurológicas, existe una necesidad cada vez mayor de la aplicación de tecnologÃas proteómicas que puedan generar lecturas potenciales de biomarcadores para una mejor gestión clÃnica, asà como para el desarrollo de nuevos medicamentos por parte de las empresas farmacéuticas en dificultades. . Este libro describe el uso paso a paso de métodos proteómicos como la electroforesis en gel bidimensional, el inmunoensayo múltiple, la cromatografÃa lÃquida, la espectrometrÃa de masas (LC-MS) y el monitoreo selectivo de reacciones MS, para aumentar nuestra comprensión de estas enfermedades, con lo último. objetivo de mejorar la atención al paciente. El volumen será de gran interés para cientÃficos clÃnicos, médicos y cientÃficos de compañÃas farmacéuticas, ya que brinda información sobre las últimas tecnologÃas que permiten la revolución de la medicina personalizada. Es de interés directo para los cientÃficos de biomarcadores tanto técnicos como de laboratorio, ya que brinda instrucciones paso a paso sobre cómo llevar a cabo cada uno de los protocolos. También es de interés para los investigadores, ya que cada técnica se presentará en el contexto de un trastorno neurológico especÃfico, incluida la enfermedad de Alzheimer, la esclerosis múltiple, los trastornos del espectro autista, la esquizofrenia, el trastorno depresivo mayor y el trastorno bipolar. Finalmente, también resaltará los futuros esfuerzos de investigación en este campo, que se esfuerzan por convertir las plataformas proteómicas en dispositivos portátiles que puedan usarse en un entorno de atención y devolver resultados de diagnóstico dentro del plazo de una visita al hospital. médico general. Nota de contenido: Preface – Proteomic studies in psychiatric disease and neurological disorders -- Part 1: REVIEWS -- Application of proteomic techniques for improved stratification and treatment of schizophrenia patients -- Multiplexing biomarker methods, proteomics and considerations for Alzheimer's disease -- What have proteomic studies taught us about novel drug targets in autism? -- Application of proteomic approaches to accelerate drug development for psychiatric disorders -- Proteomic biomarker identification in cerebrospinal fluid for leptomeningeal metastases with neurological complications -- Connecting brain proteomics with behavioural neuroscience in translational animal models of neuropsychiatric disorders -- LC-MSE for qualitative and quantitative proteomicstudies of psychiatric disorders -- The utility of multiplex assays for identification of proteomic signatures in psychiatry -- Part 2: PROTOCOLS -- Blood sampling and preparation procedures for proteomic biomarker studies of psychiatric disorders -- Multiplex immunoassay profiling of serum in psychiatric disorders -- Sequential immunopreciptation of secretory vesicle proteins from biosynthetically-labelled cells -- 2d gel electrophoresis of insulin secretory granule proteins from biosynthetically-labelled pancreatic islets -- Two-dimensional gel electrophoresis: a reference protocol -- A two-dimensional difference gel electrophoresis (2D-DIGE) protocol for studies of neural precursor cells -- Identifying biomarker candidates in the blood plasma or serum proteome -- Selective reaction monitoring mass spectrometry for quantitation of glycolytic enzymes in post-mortem brain samples -- A selected reaction monitoring mass spectrometry protocol for validation of proteomic biomarker candidates in studies of psychiatric disorders -- Application of iTRAQ shotgun proteomics for measurement of brain proteins in studies of psychiatric disorders -- Co-immunoprecipitation for deciphering protein interactomes -- Sequential co-immunopreciptation and immunoblot approach to determine oligomerisation of G-protein coupled receptors -- A protocol for producing the maternal low protein rat model: a tool for pre-clinical proteomic studies -- A clinical study protocol to identify serum biomarkers predictive of response to antipsychotics in schizophrenia patients -- Generation of the acute phencyclidine rat model for proteomic studies of schizophrenia A protocol for generation of a corticosterone model of psychiatric disorders -- MK-801-treated oligodendrocytes as a cellular model to study schizophrenia -- Combining patient-reprogrammed neural cells and proteomics as a model to study psychiatric disorders -- SILAC mass spectrometry profiling: a psychiatric disorder perspective -- Preparation of peripheral blood mononuclear cells (PBMCs) as a model for proteomic studies psychiatric disorders -- Proteomic profiling of skin fibroblasts as a model of schizophrenia Proteomic profiling of the pituitary gland in studies of psychiatric disorders -- Development of an assay for measuring proprotein-conversion activity on a multiplex magnetic bead-based array platform -- Phenotyping multiple subsets of immune cells in situ in formalin-fixed, paraffin-embedded tissue sections -- Lab-on-a-chip proteomic assays for psychiatric disorders -- Development of a user-friendly app for testing blood coagulation status in schizophrenia patients -- Part 3:FUTURE PERSPECTIVES -- Proteomic approaches to enable point-of-care testing and personalized medicine for psychiatric disorders. Tipo de medio : Computadora Summary : Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by stepinstructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
TÃtulo : Reviews on Biomarker Studies in Aging and Anti-Aging Research Tipo de documento: documento electrónico Autores: Guest, Paul C., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2019 Número de páginas: VIII, 274 p. 26 ilustraciones, 18 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-25650-0 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: ProteÃnas Bioinformática Genética Médica BioquÃmica de proteÃnas BiologÃa Computacional y de Sistemas Clasificación: 572.6 Resumen: Utilizando enfoques tanto epidemiológicos como de organismos modelo, hemos obtenido nuevos conocimientos sobre los aspectos fisiológicos y moleculares del envejecimiento, lo que ha llevado a avances significativos en posibles estrategias antienvejecimiento. Reseñas sobre estudios de biomarcadores en la investigación sobre el envejecimiento y el antienvejecimiento presenta una serie de revisiones sobre diversos aspectos de la investigación sobre el envejecimiento y las enfermedades relacionadas con la edad, junto con varios métodos que han demostrado avances como posibles enfoques antienvejecimiento. El libro está dirigido a investigadores en las áreas del envejecimiento y las enfermedades crónicas, asà como a cientÃficos clÃnicos, médicos y las principales compañÃas farmacéuticas. Proporciona información importante sobre los mecanismos de la enfermedad y cada capÃtulo se presenta en el contexto del proceso de envejecimiento, enfermedades crónicas especÃficas o diferentes áreas terapéuticas. Nota de contenido: Of Mice, Whales, Jellyfish and Men: In Pursuit of Increased Longevity -- Effects on Glial Cell Glycolysis in Schizophrenia: an Advanced Aging Phenotype? -- Aging Biomarkers and Novel Targets for Anti-Aging Interventions -- Sex Differences in Aging and Associated Biomarkers -- The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders -- Coenzyme Q10 Supplementation in Fibrosis and Aging -- Dietary Restriction, Cardiovascular Aging and Age-related Cardiovascular Diseases: A Review of the Evidence -- Gut Microbiota and Microbiota-Related Metabolites as Possible Biomarkers of Cognitive Aging -- The Impact of Herbal Products in the Prevention, Regeneration and Delay of Skin Aging -- Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging? -- From White to Brown – Adipose Tissue is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice -- The Cytoskeleton as a Modulator of Aging and Neurodegeneration -- Metabolic Biomarkers in Aging and Anti-Aging Research. Tipo de medio : Computadora Summary : Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Reviews on Biomarker Studies in Aging and Anti-Aging Research [documento electrónico] / Guest, Paul C., . - 1 ed. . - [s.l.] : Springer, 2019 . - VIII, 274 p. 26 ilustraciones, 18 ilustraciones en color.
ISBN : 978-3-030-25650-0
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: ProteÃnas Bioinformática Genética Médica BioquÃmica de proteÃnas BiologÃa Computacional y de Sistemas Clasificación: 572.6 Resumen: Utilizando enfoques tanto epidemiológicos como de organismos modelo, hemos obtenido nuevos conocimientos sobre los aspectos fisiológicos y moleculares del envejecimiento, lo que ha llevado a avances significativos en posibles estrategias antienvejecimiento. Reseñas sobre estudios de biomarcadores en la investigación sobre el envejecimiento y el antienvejecimiento presenta una serie de revisiones sobre diversos aspectos de la investigación sobre el envejecimiento y las enfermedades relacionadas con la edad, junto con varios métodos que han demostrado avances como posibles enfoques antienvejecimiento. El libro está dirigido a investigadores en las áreas del envejecimiento y las enfermedades crónicas, asà como a cientÃficos clÃnicos, médicos y las principales compañÃas farmacéuticas. Proporciona información importante sobre los mecanismos de la enfermedad y cada capÃtulo se presenta en el contexto del proceso de envejecimiento, enfermedades crónicas especÃficas o diferentes áreas terapéuticas. Nota de contenido: Of Mice, Whales, Jellyfish and Men: In Pursuit of Increased Longevity -- Effects on Glial Cell Glycolysis in Schizophrenia: an Advanced Aging Phenotype? -- Aging Biomarkers and Novel Targets for Anti-Aging Interventions -- Sex Differences in Aging and Associated Biomarkers -- The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders -- Coenzyme Q10 Supplementation in Fibrosis and Aging -- Dietary Restriction, Cardiovascular Aging and Age-related Cardiovascular Diseases: A Review of the Evidence -- Gut Microbiota and Microbiota-Related Metabolites as Possible Biomarkers of Cognitive Aging -- The Impact of Herbal Products in the Prevention, Regeneration and Delay of Skin Aging -- Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging? -- From White to Brown – Adipose Tissue is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice -- The Cytoskeleton as a Modulator of Aging and Neurodegeneration -- Metabolic Biomarkers in Aging and Anti-Aging Research. Tipo de medio : Computadora Summary : Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
