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Autor Denton, Christopher P. |
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TÃtulo : Atlas of Ulcers in Systemic Sclerosis : Diagnosis and Management Tipo de documento: documento electrónico Autores: Matucci-Cerinic, Marco, ; Denton, Christopher P., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2019 Número de páginas: XI, 238 p. 58 ilustraciones en color. ISBN/ISSN/DL: 978-3-319-98477-3 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: ReumatologÃa DermatologÃa Vasos sanguineos AngiologÃa Clasificación: 616.723 Resumen: Este Atlas examina las úlceras cutáneas en pacientes afectados por esclerosis sistémica. Aunque no ponen en peligro la vida, las úlceras digitales causan un dolor enorme, afectan la función y la calidad de vida y pueden provocar complicaciones locales graves como gangrena, osteomielitis y pérdida permanente de tejido. El conocimiento y comprensión de estas úlceras es fundamental en la práctica diaria para llegar a un diagnóstico precoz preciso, un análisis correcto de las caracterÃsticas de las úlceras y un tratamiento directo y sistemático adecuado. Con ese fin, este libro describe todas las caracterÃsticas principales de las úlceras cutáneas en la esclerosis sistemática, incluida la clasificación, evaluación y categorización. Ricamente ilustrado para uso práctico, Atlas de úlceras en la esclerosis sistémica: diagnóstico y tratamiento es un recurso esencial para médicos y profesionales afines, residentes y estudiantes de posgrado en reumatologÃa, dermatologÃa y angiologÃa. Nota de contenido: Part I. Definition and Classification -- Chapter 1. Defining Digital Ulcers in Systemic Sclerosis - The State of the Art -- Chapter 2. Digital Ulcerations and Classification of SSc Subsets and Overlap Syndromes -- Chapter 3. Classification of Digital and Lower Limb Ulcers in SSc -- Part II. Pathobiology of Digital Ulcers -- Chapter 4. Vascular Mechanisms of Systemic Sclerosis -- Chapter 5. Introduction to Wound Healing and Tissue Repair -- Part III. Microvascular Modifications and Ulcers -- Chapter 6. Raynaud's Phenomenon and Ulcers -- Chapter 7. Capillary Microscopy -- Chapter 8. Digital Ulcers, Vasculopathy and Internal Organ Involvement -- Part IV. Complications -- Chapter 9. Fistulas -- Chapter 10. Infections, Cellulitis and Osteomyelitis -- Chapter 11. Digital Loss (Gangrene, Amputation, Autoamputation) -- Chapter 12. Pain -- Chapter 13. Clinical Impact of Digital Ulcers -- Chapter 14. Calcinosis -- Part V. General Approach to Digital Ulceration – Algorithm -- Chapter 15. The Team and the Assessment -- Chapter 16. Diagnostic Tools -- Part VI. Differential Diagnosis -- Chapter 17. Differential Diagnosis – Vasculitis, Rheumatoid Arthritis, Behçet's Disease, Thromboembolism -- Part VII. The Local Treatment of Skin Ulcers in Systemic Sclerosis -- Chapter 18. The Local Treatment – Methodology, Debridement and Wound Bed Preparation -- Chapter 19. Wound Dressing for Digital Ulcers in systemic sclerosis -- Part VIII . The Systemic Treatment of Skin Ulcers in Systemic Sclerosis -- Chapter 20. Ulcer Healing and Prevention in Systemic Sclerosis -- Chapter 21. Surgical Approaches Including Sympathectomy -- Chapter 22. Antibiotic Treatment -- Chapter 23. Alternative Therapeutic Approaches in Skin Ulcers Due to Systemic Sclerosis -- Part IX. Future Strategies - Regenerative Medicine -- Chapter 24. Adipose Derived Stem Cells to Facilitate Ulcer Healing - Future Strategies -- Part X. Atlas -- Chapter 25. Atlas of Digital Ulcers and Lesions. Tipo de medio : Computadora Summary : This Atlas examines skin ulcers in patients affected by systemic sclerosis. Although they are not life threatening, digital ulcers cause enormous pain, impact function and quality of life, and can lead to serious local complications such as gangrene, osteomyelitis, and permanent tissue loss. Knowledge and understanding of these ulcers is pivotal in everyday practice in order to arrive at an accurate early diagnosis, a correct analysis of ulcer characteristics, and an appropriate direct and systematic treatment. To that end, this book describes all the major characteristics of skin ulcers in systematic sclerosis, including classification, evaluation, and categorization. Richly illustrated for practical use, Atlas of Ulcers in Systemic Sclerosis: Diagnosis and Management is an essential resource for physicians and related professionals, residents, and graduate students in rheumatology, dermatology, and angiology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Atlas of Ulcers in Systemic Sclerosis : Diagnosis and Management [documento electrónico] / Matucci-Cerinic, Marco, ; Denton, Christopher P., . - 1 ed. . - [s.l.] : Springer, 2019 . - XI, 238 p. 58 ilustraciones en color.
ISBN : 978-3-319-98477-3
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: ReumatologÃa DermatologÃa Vasos sanguineos AngiologÃa Clasificación: 616.723 Resumen: Este Atlas examina las úlceras cutáneas en pacientes afectados por esclerosis sistémica. Aunque no ponen en peligro la vida, las úlceras digitales causan un dolor enorme, afectan la función y la calidad de vida y pueden provocar complicaciones locales graves como gangrena, osteomielitis y pérdida permanente de tejido. El conocimiento y comprensión de estas úlceras es fundamental en la práctica diaria para llegar a un diagnóstico precoz preciso, un análisis correcto de las caracterÃsticas de las úlceras y un tratamiento directo y sistemático adecuado. Con ese fin, este libro describe todas las caracterÃsticas principales de las úlceras cutáneas en la esclerosis sistemática, incluida la clasificación, evaluación y categorización. Ricamente ilustrado para uso práctico, Atlas de úlceras en la esclerosis sistémica: diagnóstico y tratamiento es un recurso esencial para médicos y profesionales afines, residentes y estudiantes de posgrado en reumatologÃa, dermatologÃa y angiologÃa. Nota de contenido: Part I. Definition and Classification -- Chapter 1. Defining Digital Ulcers in Systemic Sclerosis - The State of the Art -- Chapter 2. Digital Ulcerations and Classification of SSc Subsets and Overlap Syndromes -- Chapter 3. Classification of Digital and Lower Limb Ulcers in SSc -- Part II. Pathobiology of Digital Ulcers -- Chapter 4. Vascular Mechanisms of Systemic Sclerosis -- Chapter 5. Introduction to Wound Healing and Tissue Repair -- Part III. Microvascular Modifications and Ulcers -- Chapter 6. Raynaud's Phenomenon and Ulcers -- Chapter 7. Capillary Microscopy -- Chapter 8. Digital Ulcers, Vasculopathy and Internal Organ Involvement -- Part IV. Complications -- Chapter 9. Fistulas -- Chapter 10. Infections, Cellulitis and Osteomyelitis -- Chapter 11. Digital Loss (Gangrene, Amputation, Autoamputation) -- Chapter 12. Pain -- Chapter 13. Clinical Impact of Digital Ulcers -- Chapter 14. Calcinosis -- Part V. General Approach to Digital Ulceration – Algorithm -- Chapter 15. The Team and the Assessment -- Chapter 16. Diagnostic Tools -- Part VI. Differential Diagnosis -- Chapter 17. Differential Diagnosis – Vasculitis, Rheumatoid Arthritis, Behçet's Disease, Thromboembolism -- Part VII. The Local Treatment of Skin Ulcers in Systemic Sclerosis -- Chapter 18. The Local Treatment – Methodology, Debridement and Wound Bed Preparation -- Chapter 19. Wound Dressing for Digital Ulcers in systemic sclerosis -- Part VIII . The Systemic Treatment of Skin Ulcers in Systemic Sclerosis -- Chapter 20. Ulcer Healing and Prevention in Systemic Sclerosis -- Chapter 21. Surgical Approaches Including Sympathectomy -- Chapter 22. Antibiotic Treatment -- Chapter 23. Alternative Therapeutic Approaches in Skin Ulcers Due to Systemic Sclerosis -- Part IX. Future Strategies - Regenerative Medicine -- Chapter 24. Adipose Derived Stem Cells to Facilitate Ulcer Healing - Future Strategies -- Part X. Atlas -- Chapter 25. Atlas of Digital Ulcers and Lesions. Tipo de medio : Computadora Summary : This Atlas examines skin ulcers in patients affected by systemic sclerosis. Although they are not life threatening, digital ulcers cause enormous pain, impact function and quality of life, and can lead to serious local complications such as gangrene, osteomyelitis, and permanent tissue loss. Knowledge and understanding of these ulcers is pivotal in everyday practice in order to arrive at an accurate early diagnosis, a correct analysis of ulcer characteristics, and an appropriate direct and systematic treatment. To that end, this book describes all the major characteristics of skin ulcers in systematic sclerosis, including classification, evaluation, and categorization. Richly illustrated for practical use, Atlas of Ulcers in Systemic Sclerosis: Diagnosis and Management is an essential resource for physicians and related professionals, residents, and graduate students in rheumatology, dermatology, and angiology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Practical Management of Systemic Sclerosis in Clinical Practice / Matucci-Cerinic, Marco ; Denton, Christopher P.
TÃtulo : Practical Management of Systemic Sclerosis in Clinical Practice Tipo de documento: documento electrónico Autores: Matucci-Cerinic, Marco, ; Denton, Christopher P., Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2021 Número de páginas: VII, 399 p. 38 ilustraciones, 30 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-53736-4 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: ReumatologÃa InmunologÃa Atención primaria (Medicina) NefrologÃa GastroenterologÃa Medicina de Atención Primaria Clasificación: 616.723 Resumen: Este libro proporciona una guÃa práctica para manejar una variedad de problemas que enfrenta el médico en el manejo de pacientes con esclerosis sistémica. Los capÃtulos adoptan un enfoque orientado a los problemas para ayudar al lector a superar las posibles barreras que pueden surgir al trabajar con diferentes especialidades médicas. Se presentan estrategias de manejo para una amplia gama de afecciones, incluido el derrame pericárdico y pleural, el sÃndrome seco, la calcinosis y el estómago en sandÃa. Manejo práctico de la esclerosis sistémica en la práctica clÃnica describe una variedad de problemas y elementos clÃnicos que enfrentan una variedad de profesionales médicos que tratan con estos pacientes. Es un recurso valioso para reumatólogos, inmunólogos, enfermeras especialistas y profesionales de atención primaria. . Nota de contenido: Scleroderma Renal Crisis and Acute Kidney Injury -- Chronic Kidney Disease in Scleroderma -- Anemia -- Breathlessness -- Fatigue -- Itch -- Pain and Tenosynovitis, Tendon Friction Rubs -- Raynaud's -- Critical Ischemia -- Digital Ulcers -- Lower Limb Ulcers -- Decline in PFT -- Arrhytmias -- Pericardial and Pleural Effusion -- Constipation -- Incontinence -- Bloating -- GE reflux -- Diarrhea -- Watermelon Stomach -- Malnutrition -- Calcinosis -- Pregnancy -- Sicca Syndrome -- Sexual dysfunction -- Transitional care for juvenile onset systemic sclerosis -- Assessment for HSCT -- Very early disease - VEDOSS type case -- Primary Biliary Cholangitis -- Hand Arthritis -- Contractures -- Tendon Friction Rubs -- Interpretation of the Modification of Laboratory Parameters. . Tipo de medio : Computadora Summary : This book provides a practical guide for managing a variety of problems encountered by the clinician in managing patients with systemic sclerosis. Chapters take a problem-orientated approach to help the reader cut through potential barriers that can arise when working with different medical specialities. Management strategies for a broad range of conditions, including pericardial and pleural effusion, sicca syndrome, calcinosis and watermelon stomach, are presented. Practical Management of Systemic Sclerosis in Clinical Practice describes a range of problems and clinical items encountered by a variety of medical professionals who encounter these patients. It is a valuable resource for rheumatologists, immunologists, specialist nurses and primary care professionals. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Practical Management of Systemic Sclerosis in Clinical Practice [documento electrónico] / Matucci-Cerinic, Marco, ; Denton, Christopher P., . - 1 ed. . - [s.l.] : Springer, 2021 . - VII, 399 p. 38 ilustraciones, 30 ilustraciones en color.
ISBN : 978-3-030-53736-4
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: ReumatologÃa InmunologÃa Atención primaria (Medicina) NefrologÃa GastroenterologÃa Medicina de Atención Primaria Clasificación: 616.723 Resumen: Este libro proporciona una guÃa práctica para manejar una variedad de problemas que enfrenta el médico en el manejo de pacientes con esclerosis sistémica. Los capÃtulos adoptan un enfoque orientado a los problemas para ayudar al lector a superar las posibles barreras que pueden surgir al trabajar con diferentes especialidades médicas. Se presentan estrategias de manejo para una amplia gama de afecciones, incluido el derrame pericárdico y pleural, el sÃndrome seco, la calcinosis y el estómago en sandÃa. Manejo práctico de la esclerosis sistémica en la práctica clÃnica describe una variedad de problemas y elementos clÃnicos que enfrentan una variedad de profesionales médicos que tratan con estos pacientes. Es un recurso valioso para reumatólogos, inmunólogos, enfermeras especialistas y profesionales de atención primaria. . Nota de contenido: Scleroderma Renal Crisis and Acute Kidney Injury -- Chronic Kidney Disease in Scleroderma -- Anemia -- Breathlessness -- Fatigue -- Itch -- Pain and Tenosynovitis, Tendon Friction Rubs -- Raynaud's -- Critical Ischemia -- Digital Ulcers -- Lower Limb Ulcers -- Decline in PFT -- Arrhytmias -- Pericardial and Pleural Effusion -- Constipation -- Incontinence -- Bloating -- GE reflux -- Diarrhea -- Watermelon Stomach -- Malnutrition -- Calcinosis -- Pregnancy -- Sicca Syndrome -- Sexual dysfunction -- Transitional care for juvenile onset systemic sclerosis -- Assessment for HSCT -- Very early disease - VEDOSS type case -- Primary Biliary Cholangitis -- Hand Arthritis -- Contractures -- Tendon Friction Rubs -- Interpretation of the Modification of Laboratory Parameters. . Tipo de medio : Computadora Summary : This book provides a practical guide for managing a variety of problems encountered by the clinician in managing patients with systemic sclerosis. Chapters take a problem-orientated approach to help the reader cut through potential barriers that can arise when working with different medical specialities. Management strategies for a broad range of conditions, including pericardial and pleural effusion, sicca syndrome, calcinosis and watermelon stomach, are presented. Practical Management of Systemic Sclerosis in Clinical Practice describes a range of problems and clinical items encountered by a variety of medical professionals who encounter these patients. It is a valuable resource for rheumatologists, immunologists, specialist nurses and primary care professionals. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
TÃtulo : Scleroderma : From Pathogenesis to Comprehensive Management Tipo de documento: documento electrónico Autores: Varga, John, ; Denton, Christopher P., ; Wigley, Fredrick M., ; Allanore, Yannick, ; Kuwana, Masataka, Mención de edición: 2 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2017 Número de páginas: XXXV, 743 p. 191 ilustraciones, 174 ilustraciones en color. ISBN/ISSN/DL: 978-3-319-31407-5 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: ReumatologÃa Órganos respiratorios DermatologÃa NeumologÃa Clasificación: 616.723 Resumen: Compuesta por el trabajo autorizado de expertos internacionales, esta segunda edición completamente actualizada de Escleroderma se basa en el enfoque bien considerado de la primera edición para proporcionar una sÃntesis integrada, concisa y actualizada de los conceptos actuales de patogénesis y enfoques modernos para Manejo de la esclerosis sistémica (esclerodermia). Con un enfoque multidisciplinario de la atención integral, este libro es de fácil acceso para profesionales de la salud en muchos campos. La nueva edición incluye material extenso y actualizado basado en los principales avances en el campo, con nuevos capÃtulos sobre medicina personalizada, complicaciones del cáncer, perspectivas globales sobre la esclerodermia y más. Presenta una sÃntesis sucinta y reflexiva de los conceptos patomecanicistas actuales, proporcionando una valiosa herramienta de referencia para los investigadores básicos y traslacionales que trabajan en este campo. Esclerodermia: de la patogénesis al tratamiento integral sirve como un recurso esencial e integral para reumatólogos, neumólogos, cardiólogos, gastroenterólogos, nefrólogos y todos aquellos involucrados en el cuidado de pacientes con esclerodermia. Nota de contenido: Section I. Introduction -- Historical Perspective of Scleroderma -- Section II. Epidemiology, Genetics and Classification -- Epidemiology, Environmental and Infectious Risk Factors -- Genetic Factors -- Disease Subsets in Clinical Practice -- Evolving Concepts of Diagnosis and Classification -- Overlap Syndromes -- Juvenile Localized and Systemic Scleroderma -- Morphea (Localized Scleroderma) -- Scleroderma Mimics -- Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis -- Section III: The Biological Basis of Systemic Sclerosis -- Introduction: The Etiopathogenesis of Systemic Sclerosis: An Integrated Overview -- Pathology of Systemic Sclerosis -- Inflammation and Immunity -- Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis -- The Clinical Aspects of Autoantibodies -- Mechanisms of Vascular Disease -- Biomarkers in Systemic Sclerosis -- Pathophysiology of Fibrosis in Systemic Sclerosis -- Overview of Animal Models -- Section IV. Cardiovascular Manifestations and Management -- Raynaud's Phenomenon, Digital Ulcers, and Nailfold Capillaroscopy -- Renal Crisis and Other Renal Manifestations of Scleroderma -- Cardiac Involvement -- Section V. Pulmonary Manifestations and Management -- Overview of Lung Involvement: Diagnosis, Differential Diagnosis, and Monitoring -- Clinical Assessment of Lung Disease -- Treatment of Interstitial Lung Disease -- Pathogenesis of Pulmonary Arterial Hypertension -- Clinical Assessment of Pulmonary Hypertension -- The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis -- Section VI. Gastrointestinal Manifestations and Management -- Overview of Gastrointestinal Tract Involvement -- Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis -- Small and Large Intestinal Involvement and Nutritional Issues -- Section VII. Skin, Musculoskeletal and Other Complications -- Calcinosis -- Evaluation and Management of Skin Disease -- Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma -- Skeletal Muscle Involvement -- Tendons, Joints, and Bone -- Cancer in Systemic Sclerosis -- Overlooked Manifestations -- Pregnancy -- Section VIII: Management and Outcome Assessment -- Introduction to Section VIII: Management and Outcome Assessment -- Immunomodulatory, Immunoablative, and Biologic Therapies -- Investigative Approaches to Drug Therapy -- Drug Development and Regulatory Considerations for SSc Therapies -- Physical and Occupational Therapy -- Psychosocial Issues and Care for Patients with Systemic Sclerosis -- Clinical Trial Design in Systemic Sclerosis -- Measuring Disease Activity and Outcomes in Clinical Trials -- Innovative Approaches to Clinical Trials in Systemic Sclerosis -- Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis -- Section IX. Case Studies: Approach to Complex Clinical Problems -- Managing the Ischemic Finger in Scleroderma -- Scleroderma Renal Crisis -- Rapid Diffuse Skin Disease with Progressive Joint Contractures -- Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy -- Pseudo-obstruction with Malabsorption and Malnutrition -- Progressive Interstitial Lung Disease Non-Response to Cyclophosphamide -- Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes -- Managing Complicated Digital Ulcers . Tipo de medio : Computadora Summary : Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Scleroderma : From Pathogenesis to Comprehensive Management [documento electrónico] / Varga, John, ; Denton, Christopher P., ; Wigley, Fredrick M., ; Allanore, Yannick, ; Kuwana, Masataka, . - 2 ed. . - [s.l.] : Springer, 2017 . - XXXV, 743 p. 191 ilustraciones, 174 ilustraciones en color.
ISBN : 978-3-319-31407-5
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: ReumatologÃa Órganos respiratorios DermatologÃa NeumologÃa Clasificación: 616.723 Resumen: Compuesta por el trabajo autorizado de expertos internacionales, esta segunda edición completamente actualizada de Escleroderma se basa en el enfoque bien considerado de la primera edición para proporcionar una sÃntesis integrada, concisa y actualizada de los conceptos actuales de patogénesis y enfoques modernos para Manejo de la esclerosis sistémica (esclerodermia). Con un enfoque multidisciplinario de la atención integral, este libro es de fácil acceso para profesionales de la salud en muchos campos. La nueva edición incluye material extenso y actualizado basado en los principales avances en el campo, con nuevos capÃtulos sobre medicina personalizada, complicaciones del cáncer, perspectivas globales sobre la esclerodermia y más. Presenta una sÃntesis sucinta y reflexiva de los conceptos patomecanicistas actuales, proporcionando una valiosa herramienta de referencia para los investigadores básicos y traslacionales que trabajan en este campo. Esclerodermia: de la patogénesis al tratamiento integral sirve como un recurso esencial e integral para reumatólogos, neumólogos, cardiólogos, gastroenterólogos, nefrólogos y todos aquellos involucrados en el cuidado de pacientes con esclerodermia. Nota de contenido: Section I. Introduction -- Historical Perspective of Scleroderma -- Section II. Epidemiology, Genetics and Classification -- Epidemiology, Environmental and Infectious Risk Factors -- Genetic Factors -- Disease Subsets in Clinical Practice -- Evolving Concepts of Diagnosis and Classification -- Overlap Syndromes -- Juvenile Localized and Systemic Scleroderma -- Morphea (Localized Scleroderma) -- Scleroderma Mimics -- Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis -- Section III: The Biological Basis of Systemic Sclerosis -- Introduction: The Etiopathogenesis of Systemic Sclerosis: An Integrated Overview -- Pathology of Systemic Sclerosis -- Inflammation and Immunity -- Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis -- The Clinical Aspects of Autoantibodies -- Mechanisms of Vascular Disease -- Biomarkers in Systemic Sclerosis -- Pathophysiology of Fibrosis in Systemic Sclerosis -- Overview of Animal Models -- Section IV. Cardiovascular Manifestations and Management -- Raynaud's Phenomenon, Digital Ulcers, and Nailfold Capillaroscopy -- Renal Crisis and Other Renal Manifestations of Scleroderma -- Cardiac Involvement -- Section V. Pulmonary Manifestations and Management -- Overview of Lung Involvement: Diagnosis, Differential Diagnosis, and Monitoring -- Clinical Assessment of Lung Disease -- Treatment of Interstitial Lung Disease -- Pathogenesis of Pulmonary Arterial Hypertension -- Clinical Assessment of Pulmonary Hypertension -- The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis -- Section VI. Gastrointestinal Manifestations and Management -- Overview of Gastrointestinal Tract Involvement -- Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis -- Small and Large Intestinal Involvement and Nutritional Issues -- Section VII. Skin, Musculoskeletal and Other Complications -- Calcinosis -- Evaluation and Management of Skin Disease -- Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma -- Skeletal Muscle Involvement -- Tendons, Joints, and Bone -- Cancer in Systemic Sclerosis -- Overlooked Manifestations -- Pregnancy -- Section VIII: Management and Outcome Assessment -- Introduction to Section VIII: Management and Outcome Assessment -- Immunomodulatory, Immunoablative, and Biologic Therapies -- Investigative Approaches to Drug Therapy -- Drug Development and Regulatory Considerations for SSc Therapies -- Physical and Occupational Therapy -- Psychosocial Issues and Care for Patients with Systemic Sclerosis -- Clinical Trial Design in Systemic Sclerosis -- Measuring Disease Activity and Outcomes in Clinical Trials -- Innovative Approaches to Clinical Trials in Systemic Sclerosis -- Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis -- Section IX. Case Studies: Approach to Complex Clinical Problems -- Managing the Ischemic Finger in Scleroderma -- Scleroderma Renal Crisis -- Rapid Diffuse Skin Disease with Progressive Joint Contractures -- Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy -- Pseudo-obstruction with Malabsorption and Malnutrition -- Progressive Interstitial Lung Disease Non-Response to Cyclophosphamide -- Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes -- Managing Complicated Digital Ulcers . Tipo de medio : Computadora Summary : Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]
