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TÃtulo : Integrated Omics Approaches to Infectious Diseases Tipo de documento: documento electrónico Autores: Hameed, Saif, ; Fatima, Zeeshan, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2021 Número de páginas: XIX, 542 p. 78 ilustraciones, 69 ilustraciones en color. ISBN/ISSN/DL: 978-981-1606915-- Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: VirologÃa MicrobiologÃa médica Enfermedad ParasitologÃa Clasificación: 616.071 Resumen: Este libro examina las aplicaciones de enfoques multiómicos para comprender la etiologÃa, patogénesis y las interacciones huésped-patógeno de las enfermedades. También analiza los mecanismos genéticos, inmunológicos y metabólicos subyacentes a las infecciones. El libro también explora enfoques de genómica, transcriptómica, traslacional y metabolómica para comprender la patogénesis e identificar posibles objetivos farmacológicos. Revisa el papel de la reprogramación epigenética en la configuración de las interacciones huésped-patógeno y presenta la aplicación de la bioinformática en la identificación de objetivos farmacológicos. Además, examina las aplicaciones potenciales de la secuenciación de ARN y la elaboración de perfiles de ARN no codificante para identificar la patogénesis. Por último, ofrece los desafÃos actuales, los avances tecnológicos y las perspectivas del uso de tecnologÃas multiómicas en biologÃa infecciosa. Nota de contenido: Chapter 1. Geno-Informatics for Prediction of Virulence and Drug Resistance in Bacterial Pathogens -- Chapter 2. Next Generation Sequencing: Challenges and Opportunities in Tuberculosis Research -- Chapter 3. Deciphering the role of epigenetic reprogramming in host-pathogen interactions -- Chapter 4. Genomic evidence provides the understanding of SARS-CoV-2 composition, divergence and diagnosis -- Chapter 5. Importance of Next Generation Sequencing in Viral Diagnostics -- Chapter 6. Bioinformatics application in CoVID19 -- Chapter 7. Emerging Transcriptomics approaches to decipher Mycobacterial complexities -- Chapter 8. Microarrays: A road map to uncover host pathogen interactions -- Chapter 9. Transcriptional Approach in the Identification of Drug Targets in Candida spp -- Chapter 10. Non-Coding RNA profiling: Potential Application in Infectious Diseases -- Chapter 11. RNA-seq analysis strategies to understand viral pathogenesis -- Chapter 12. Various Transcriptomic approaches & their applications to study small non-coding RNAs in Dengue and other viruses -- Chapter 13. Transcriptomic Approaches in Understanding Sars-COV-2 Infection -- Chapter 14. miRNA target prediction: Overview and applications -- Chapter 15. A Glimpse into Peptidomic Approach -- Chapter 16. Molecular mechanism of action of antimicrobial agents against clinically important human pathogens: A proteomic approach -- Chapter 17. Exploration of the mycobacterial proteome in the pathogenesis of TB: A perspective -- Chapter 18. Pathogenesis of Staphylococcus aureus and proteomic strategies for the identification of drug targets -- Chapter 19. Proteomics in the study of Host-Pathogen interactions -- Chapter 20. Significance of post-translational modifications in Apicomplexan parasites -- Chapter 21. An introduction to computational pipelines for analyzing untargeted metabolomics data for Leishmaniasis -- Chapter 22. Metabolomics: PromisingTool to Study Disease Biomarkers and Host-Pathogen Interactions -- Chapter 23. Lipidomics to study the role of lipid droplets in host-pathogen interactions -- Chapter 24. Lipid structure, function and lipidomic applications -- Chapter 25. Nanoparticles as Therapeutic Nanocargos affecting Epigenome of Microbial Biofilms -- Chapter 26. Malaria in the era of OMICS: Challenges and Way forward -- Chapter 27. Omics Approaches for Infectious Diseases -- Chapter 28. Pathogen-Omics: challenges and prospects in research and clinical settings. Tipo de medio : Computadora Summary : This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Integrated Omics Approaches to Infectious Diseases [documento electrónico] / Hameed, Saif, ; Fatima, Zeeshan, . - 1 ed. . - Singapore [Malasia] : Springer, 2021 . - XIX, 542 p. 78 ilustraciones, 69 ilustraciones en color.
ISBN : 978-981-1606915--
Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos.
Idioma : Inglés (eng)
Palabras clave: VirologÃa MicrobiologÃa médica Enfermedad ParasitologÃa Clasificación: 616.071 Resumen: Este libro examina las aplicaciones de enfoques multiómicos para comprender la etiologÃa, patogénesis y las interacciones huésped-patógeno de las enfermedades. También analiza los mecanismos genéticos, inmunológicos y metabólicos subyacentes a las infecciones. El libro también explora enfoques de genómica, transcriptómica, traslacional y metabolómica para comprender la patogénesis e identificar posibles objetivos farmacológicos. Revisa el papel de la reprogramación epigenética en la configuración de las interacciones huésped-patógeno y presenta la aplicación de la bioinformática en la identificación de objetivos farmacológicos. Además, examina las aplicaciones potenciales de la secuenciación de ARN y la elaboración de perfiles de ARN no codificante para identificar la patogénesis. Por último, ofrece los desafÃos actuales, los avances tecnológicos y las perspectivas del uso de tecnologÃas multiómicas en biologÃa infecciosa. Nota de contenido: Chapter 1. Geno-Informatics for Prediction of Virulence and Drug Resistance in Bacterial Pathogens -- Chapter 2. Next Generation Sequencing: Challenges and Opportunities in Tuberculosis Research -- Chapter 3. Deciphering the role of epigenetic reprogramming in host-pathogen interactions -- Chapter 4. Genomic evidence provides the understanding of SARS-CoV-2 composition, divergence and diagnosis -- Chapter 5. Importance of Next Generation Sequencing in Viral Diagnostics -- Chapter 6. Bioinformatics application in CoVID19 -- Chapter 7. Emerging Transcriptomics approaches to decipher Mycobacterial complexities -- Chapter 8. Microarrays: A road map to uncover host pathogen interactions -- Chapter 9. Transcriptional Approach in the Identification of Drug Targets in Candida spp -- Chapter 10. Non-Coding RNA profiling: Potential Application in Infectious Diseases -- Chapter 11. RNA-seq analysis strategies to understand viral pathogenesis -- Chapter 12. Various Transcriptomic approaches & their applications to study small non-coding RNAs in Dengue and other viruses -- Chapter 13. Transcriptomic Approaches in Understanding Sars-COV-2 Infection -- Chapter 14. miRNA target prediction: Overview and applications -- Chapter 15. A Glimpse into Peptidomic Approach -- Chapter 16. Molecular mechanism of action of antimicrobial agents against clinically important human pathogens: A proteomic approach -- Chapter 17. Exploration of the mycobacterial proteome in the pathogenesis of TB: A perspective -- Chapter 18. Pathogenesis of Staphylococcus aureus and proteomic strategies for the identification of drug targets -- Chapter 19. Proteomics in the study of Host-Pathogen interactions -- Chapter 20. Significance of post-translational modifications in Apicomplexan parasites -- Chapter 21. An introduction to computational pipelines for analyzing untargeted metabolomics data for Leishmaniasis -- Chapter 22. Metabolomics: PromisingTool to Study Disease Biomarkers and Host-Pathogen Interactions -- Chapter 23. Lipidomics to study the role of lipid droplets in host-pathogen interactions -- Chapter 24. Lipid structure, function and lipidomic applications -- Chapter 25. Nanoparticles as Therapeutic Nanocargos affecting Epigenome of Microbial Biofilms -- Chapter 26. Malaria in the era of OMICS: Challenges and Way forward -- Chapter 27. Omics Approaches for Infectious Diseases -- Chapter 28. Pathogen-Omics: challenges and prospects in research and clinical settings. Tipo de medio : Computadora Summary : This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]