Exposure Toxicology in Caenorhabditis elegans / Wang, Dayong  

Público ISBD Ningún comentario para este registro. Título : Exposure Toxicology in Caenorhabditis elegans Tipo de documento: documento electrónico Autores: Wang, Dayong, Mención de edición: 1 ed. Editorial: Singapore [Malasia] : Springer Fecha de publicación: 2020 Número de páginas: XIX, 682 p. 447 ilustraciones, 303 ilustraciones en color. ISBN/ISSN/DL: 978-981-1561290-- Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Farmacología Clasificación: 615.90072 Resumen: Este libro se centra en la toxicología de la exposición en C. elegans. El nematodo Caenorhabditis elegans es sensible a varios tóxicos ambientales y estreses, y ha demostrado ser un modelo animal importante tanto en la toxicología molecular como en la toxicología de órganos diana. Como resultado, durante los últimos 30 años, ha habido una amplia investigación sobre la exposición a tóxicos ambientales o estreses en nematodos. Con base en los datos disponibles, el libro ofrece una introducción al sistema de exposición establecido en nematodos, discutiendo varios aspectos de los puntos finales que potencialmente pueden usarse para evaluar la toxicidad de los tóxicos ambientales o estreses. También explorando varios factores que afectan la inducción de toxicidad y la exposición a tóxicos ambientales y estreses, permite a los lectores obtener una comprensión sistemática de la toxicología de la exposición en C. elegans. Nota de contenido: 1. Exposure Durations of Environmental Stresses or Toxicants -- 2. Exposure Stages of Environmental Stresses or Toxicants -- 3. Complex Exposures to Environmental Toxicants or Stresses -- 4. Transgenerational Toxicity of Environmental Toxicants or Stresses -- 5. Exposure Routes of Environmental Toxicants -- 6. Basic Endpoints for Toxicity Assessment of Environmental Toxicants or Stresses -- 7. Endpoints for Assessing the Toxicity on Primary Targeted Organs -- 8. Endpoints for Assessing the Toxicity on Secondary Targeted Organs -- 9. Endpoints for Assessing the Toxicity on Biochemical Processes -- 10. Endpoints for Assessing the Genotoxicity and the Genetic Toxicity -- 11. Role of Exposure Dose in Toxicity Induction of Environmental Toxicants or Stresses -- 12. Role of Environmental Factors in Toxicity Induction of Environmental Toxicants or Stresses -- 13. Effects of Environmental Sample Forms on Toxicity Induction -- 14. Roles of Physicochemical Properties of Toxicants in Toxicity Induction -- 15. Roles of Environmental Media and Chemical Transformations of Environmental Toxicants in Toxicity Induction -- 16. Bioavailability, Enrichment, and Translocation of Environmental Toxicants -- 17. Susceptibility to Toxicants or Stresses Induced by Genetic Mutations -- 18. Contributors to Amplify the Toxicity of Toxicants or Stresses -- 19. Exposure to Certain Environmental Stresses -- 20. High-Throughput Toxicity Assessment -- 21. Toxicity Assessment under the Pathological Conditions. Tipo de medio : Computadora Summary : This book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Exposure Toxicology in Caenorhabditis elegans [documento electrónico] / Wang, Dayong,  . -  1 ed.  . - Singapore [Malasia] : Springer, 2020 . - XIX, 682 p. 447 ilustraciones, 303 ilustraciones en color. ISBN : 978-981-1561290-- Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Farmacología Clasificación: 615.90072 Resumen: Este libro se centra en la toxicología de la exposición en C. elegans. El nematodo Caenorhabditis elegans es sensible a varios tóxicos ambientales y estreses, y ha demostrado ser un modelo animal importante tanto en la toxicología molecular como en la toxicología de órganos diana. Como resultado, durante los últimos 30 años, ha habido una amplia investigación sobre la exposición a tóxicos ambientales o estreses en nematodos. Con base en los datos disponibles, el libro ofrece una introducción al sistema de exposición establecido en nematodos, discutiendo varios aspectos de los puntos finales que potencialmente pueden usarse para evaluar la toxicidad de los tóxicos ambientales o estreses. También explorando varios factores que afectan la inducción de toxicidad y la exposición a tóxicos ambientales y estreses, permite a los lectores obtener una comprensión sistemática de la toxicología de la exposición en C. elegans. Nota de contenido: 1. Exposure Durations of Environmental Stresses or Toxicants -- 2. Exposure Stages of Environmental Stresses or Toxicants -- 3. Complex Exposures to Environmental Toxicants or Stresses -- 4. Transgenerational Toxicity of Environmental Toxicants or Stresses -- 5. Exposure Routes of Environmental Toxicants -- 6. Basic Endpoints for Toxicity Assessment of Environmental Toxicants or Stresses -- 7. Endpoints for Assessing the Toxicity on Primary Targeted Organs -- 8. Endpoints for Assessing the Toxicity on Secondary Targeted Organs -- 9. Endpoints for Assessing the Toxicity on Biochemical Processes -- 10. Endpoints for Assessing the Genotoxicity and the Genetic Toxicity -- 11. Role of Exposure Dose in Toxicity Induction of Environmental Toxicants or Stresses -- 12. Role of Environmental Factors in Toxicity Induction of Environmental Toxicants or Stresses -- 13. Effects of Environmental Sample Forms on Toxicity Induction -- 14. Roles of Physicochemical Properties of Toxicants in Toxicity Induction -- 15. Roles of Environmental Media and Chemical Transformations of Environmental Toxicants in Toxicity Induction -- 16. Bioavailability, Enrichment, and Translocation of Environmental Toxicants -- 17. Susceptibility to Toxicants or Stresses Induced by Genetic Mutations -- 18. Contributors to Amplify the Toxicity of Toxicants or Stresses -- 19. Exposure to Certain Environmental Stresses -- 20. High-Throughput Toxicity Assessment -- 21. Toxicity Assessment under the Pathological Conditions. Tipo de medio : Computadora Summary : This book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans. . Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]

Free Radical Biology and Environmental Toxicity / Kesari, Kavindra Kumar ; Jha, Niraj Kumar  

Público ISBD Ningún comentario para este registro. Título : Free Radical Biology and Environmental Toxicity Tipo de documento: documento electrónico Autores: Kesari, Kavindra Kumar, ; Jha, Niraj Kumar, Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2021 Número de páginas: XIV, 392 p. 71 ilustraciones, 47 ilustraciones en color. ISBN/ISSN/DL: 978-3-030-83446-3 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Biología Molecular  Citología  Inmunotoxicología  Ambiente  Biología Celular  Inmunotoxicidad  Ciencias ambientales Clasificación: 615.90072 Resumen: El objetivo principal de este libro es recopilar una serie de artículos de investigación y reseñas de un grupo diverso de científicos para compartir su trabajo de investigación sobre el papel de la investigación de los radicales libres y la toxicidad ambiental. Este libro presenta varios capítulos sobre el estado del arte de los avances recientes en el campo de la toxicología celular y las manifestaciones clínicas de diversos trastornos. Los temas incluyen señalización celular, diversos factores de riesgo, fisiopatología de la instigación y distribución de enfermedades, conocimientos mecanicistas sobre la toxicidad de metales y nanopartículas, toxicidad neuronal, carcinogenicidad no genotóxica, toxicidad inmune e idiosincrásica, prevención, biomarcadores relacionados con la progresión de enfermedades y estrategias terapéuticas. En particular, este libro proporciona información valiosa para investigadores, patólogos y médicos interesados ​​en la investigación toxicológica y las alteraciones celulares, con especial énfasis en el avance terapéutico. Nota de contenido: Male infertility: a complete guide to lifestyle and environmental factors -- Use of folic acid in the treatment of oxidative-stress associated male infertility: a myth or reality? -- Methylglyoxal induced mitochondrial perturbation and neuronal toxicity in Alzheimer disease -- Free radicals-mediated oxidative damage in memory loss: Are antioxidant therapies useful? -- ROS-induced neural toxicity in Parkinson's Disease -- Cyclin-dependent Kinase in oxidative stress and development of cancer -- Radiation induced free radical formation lead to head and neck cancer -- Pathophysiology of radiations: Radiofrequency electromagnetic radiation oxidative stress and carcinogenesis -- Heavy metal contamination induced oxidative tress lead to neurodegenerative diseases -- Networking of nanoparticles toxicity in environment and possible role of ROS in disease mechanism -- Free radicals and microbes in nature -- Relevance of ROS and NOS in Leishmaniasis: A recent update -- Alcohol-induced neuronal toxicity in Alzheimer disease. Tipo de medio : Computadora Summary : The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Free Radical Biology and Environmental Toxicity [documento electrónico] / Kesari, Kavindra Kumar, ; Jha, Niraj Kumar,  . -  1 ed.  . - [s.l.] : Springer, 2021 . - XIV, 392 p. 71 ilustraciones, 47 ilustraciones en color. ISBN : 978-3-030-83446-3 Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Biología Molecular  Citología  Inmunotoxicología  Ambiente  Biología Celular  Inmunotoxicidad  Ciencias ambientales Clasificación: 615.90072 Resumen: El objetivo principal de este libro es recopilar una serie de artículos de investigación y reseñas de un grupo diverso de científicos para compartir su trabajo de investigación sobre el papel de la investigación de los radicales libres y la toxicidad ambiental. Este libro presenta varios capítulos sobre el estado del arte de los avances recientes en el campo de la toxicología celular y las manifestaciones clínicas de diversos trastornos. Los temas incluyen señalización celular, diversos factores de riesgo, fisiopatología de la instigación y distribución de enfermedades, conocimientos mecanicistas sobre la toxicidad de metales y nanopartículas, toxicidad neuronal, carcinogenicidad no genotóxica, toxicidad inmune e idiosincrásica, prevención, biomarcadores relacionados con la progresión de enfermedades y estrategias terapéuticas. En particular, este libro proporciona información valiosa para investigadores, patólogos y médicos interesados ​​en la investigación toxicológica y las alteraciones celulares, con especial énfasis en el avance terapéutico. Nota de contenido: Male infertility: a complete guide to lifestyle and environmental factors -- Use of folic acid in the treatment of oxidative-stress associated male infertility: a myth or reality? -- Methylglyoxal induced mitochondrial perturbation and neuronal toxicity in Alzheimer disease -- Free radicals-mediated oxidative damage in memory loss: Are antioxidant therapies useful? -- ROS-induced neural toxicity in Parkinson's Disease -- Cyclin-dependent Kinase in oxidative stress and development of cancer -- Radiation induced free radical formation lead to head and neck cancer -- Pathophysiology of radiations: Radiofrequency electromagnetic radiation oxidative stress and carcinogenesis -- Heavy metal contamination induced oxidative tress lead to neurodegenerative diseases -- Networking of nanoparticles toxicity in environment and possible role of ROS in disease mechanism -- Free radicals and microbes in nature -- Relevance of ROS and NOS in Leishmaniasis: A recent update -- Alcohol-induced neuronal toxicity in Alzheimer disease. Tipo de medio : Computadora Summary : The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]

Nanotoxicology in Humans and the Environment / Lead, Jamie R. ; Doak, Shareen H. ; Clift, Martin J.D  

Público ISBD Ningún comentario para este registro. Título : Nanotoxicology in Humans and the Environment Tipo de documento: documento electrónico Autores: Lead, Jamie R., ; Doak, Shareen H., ; Clift, Martin J.D, Mención de edición: 1 ed. Editorial: [s.l.] : Springer Fecha de publicación: 2021 Número de páginas: V, 259 p. 1 ilustraciones ISBN/ISSN/DL: 978-3-030-79808-6 Nota general: Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Farmacología  Ambiente  Ciencias ambientales Clasificación: 615.90072 Resumen: El libro cubre el área de la ''Nanotoxicología'' pero principalmente desde el punto de vista de la nanotoxicología en la interfaz con otras disciplinas, incluida la toxicología humana; toxicología ambiental; caracterización, dosis y transformaciones; regulación; percepciones del público y de los grupos de élite; e interacciones con la innovación. Nanotoxicología en humanos y el medio ambiente está escrito para investigadores en nanotoxicología del mundo académico, industrial, gubernamental y estudiantes de investigación. Dado el rápido desarrollo, la maduración de la disciplina y su importancia en la regulación actual y el desarrollo de la industria (por ejemplo, REACH, TSCA), el libro es muy oportuno. Nota de contenido: Overview of Nanotoxicology in Humans and the Environment: Developments.-The potential adverse effects of engineered nanomaterial exposure to human health following pulmonary, oral and dermal exposure @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ZH-CN;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;}div.WordSection1 {page:WordSection1;} -- Nanotoxicology in the Environment -- Nano-enabled consumer products Ѐ“ inventories, release, and exposures -- Factors affecting nanoparticle doseЀ“exposure and cell response -- Mapping Exposure onto Nanoscale Toxicity Measures -- Nanotoxicology and risk perception among public and elite groups -- EU Regulations and Nanotechnology Innovation. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; 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mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ZH-CN;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;}div.WordSection1 {page:WordSection. Tipo de medio : Computadora Summary : The book covers the area of 'Nanotoxicology' but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...] Nanotoxicology in Humans and the Environment [documento electrónico] / Lead, Jamie R., ; Doak, Shareen H., ; Clift, Martin J.D,  . -  1 ed.  . - [s.l.] : Springer, 2021 . - V, 259 p. 1 ilustraciones. ISBN : 978-3-030-79808-6 Libro disponible en la plataforma SpringerLink. Descarga y lectura en formatos PDF, HTML y ePub. Descarga completa o por capítulos. Idioma : Inglés (eng) Palabras clave: Toxicología  Farmacología  Ambiente  Ciencias ambientales Clasificación: 615.90072 Resumen: El libro cubre el área de la ''Nanotoxicología'' pero principalmente desde el punto de vista de la nanotoxicología en la interfaz con otras disciplinas, incluida la toxicología humana; toxicología ambiental; caracterización, dosis y transformaciones; regulación; percepciones del público y de los grupos de élite; e interacciones con la innovación. Nanotoxicología en humanos y el medio ambiente está escrito para investigadores en nanotoxicología del mundo académico, industrial, gubernamental y estudiantes de investigación. Dado el rápido desarrollo, la maduración de la disciplina y su importancia en la regulación actual y el desarrollo de la industria (por ejemplo, REACH, TSCA), el libro es muy oportuno. Nota de contenido: Overview of Nanotoxicology in Humans and the Environment: Developments.-The potential adverse effects of engineered nanomaterial exposure to human health following pulmonary, oral and dermal exposure @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ZH-CN;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;}div.WordSection1 {page:WordSection1;} -- Nanotoxicology in the Environment -- Nano-enabled consumer products Ѐ“ inventories, release, and exposures -- Factors affecting nanoparticle doseЀ“exposure and cell response -- Mapping Exposure onto Nanoscale Toxicity Measures -- Nanotoxicology and risk perception among public and elite groups -- EU Regulations and Nanotechnology Innovation. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; 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Tipo de medio : Computadora Summary : The book covers the area of 'Nanotoxicology' but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely. Enlace de acceso : https://link-springer-com.biblioproxy.umanizales.edu.co/referencework/10.1007/97 [...]

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